Hand-Held Optoacoustic System for the Localization of Mid-Depth Blood Vessels

The ability to rapidly locate blood vessels in patients is important in many clinical applications, e.g., in catheterization procedures. Optical techniques, including visual inspection, generally suffer from a reduced performance at depths below 1 mm, while ultrasound and optoacoustic tomography are...

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Main Authors: Zohar Or, Ahiad R. Levi, Yoav Hazan, Amir Rosenthal
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Photonics
Subjects:
Online Access:https://www.mdpi.com/2304-6732/9/12/907
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author Zohar Or
Ahiad R. Levi
Yoav Hazan
Amir Rosenthal
author_facet Zohar Or
Ahiad R. Levi
Yoav Hazan
Amir Rosenthal
author_sort Zohar Or
collection DOAJ
description The ability to rapidly locate blood vessels in patients is important in many clinical applications, e.g., in catheterization procedures. Optical techniques, including visual inspection, generally suffer from a reduced performance at depths below 1 mm, while ultrasound and optoacoustic tomography are better suited to a typical depth on the scale of 1 cm and require an additional spacer between the tissue and transducer in order to image the superficial structures at the focus plane. For this work, we developed a hand-held optoacoustic probe, designed for localizing blood vessels from the contact point down to a depth of 1 cm, without the use of a spacer. The probe employs a flat lens-free ultrasound array, enabling a largely depth-independent response down to a depth of 1 cm, at the expense of low elevational resolution. Specifically, while in lens-based probes, the acoustic signals from outside the focal region suffer from distortion, in our probe, only the amplitude of the signal varies with depth, thus leading to an imaging quality that is largely depth-independent in the imaged region. To facilitate miniaturization, dark-field illumination is used, whereby light scattering from the tissue is exploited to homogenize the sensitivity field.
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spelling doaj.art-eb648aa62cee4e53a5f97a05dc3fd98b2023-11-24T17:24:34ZengMDPI AGPhotonics2304-67322022-11-0191290710.3390/photonics9120907Hand-Held Optoacoustic System for the Localization of Mid-Depth Blood VesselsZohar Or0Ahiad R. Levi1Yoav Hazan2Amir Rosenthal3Electrical and Computer Engineering Department, Technion—Israel Institute of Technology, Haifa 3200003, IsraelElectrical and Computer Engineering Department, Technion—Israel Institute of Technology, Haifa 3200003, IsraelElectrical and Computer Engineering Department, Technion—Israel Institute of Technology, Haifa 3200003, IsraelElectrical and Computer Engineering Department, Technion—Israel Institute of Technology, Haifa 3200003, IsraelThe ability to rapidly locate blood vessels in patients is important in many clinical applications, e.g., in catheterization procedures. Optical techniques, including visual inspection, generally suffer from a reduced performance at depths below 1 mm, while ultrasound and optoacoustic tomography are better suited to a typical depth on the scale of 1 cm and require an additional spacer between the tissue and transducer in order to image the superficial structures at the focus plane. For this work, we developed a hand-held optoacoustic probe, designed for localizing blood vessels from the contact point down to a depth of 1 cm, without the use of a spacer. The probe employs a flat lens-free ultrasound array, enabling a largely depth-independent response down to a depth of 1 cm, at the expense of low elevational resolution. Specifically, while in lens-based probes, the acoustic signals from outside the focal region suffer from distortion, in our probe, only the amplitude of the signal varies with depth, thus leading to an imaging quality that is largely depth-independent in the imaged region. To facilitate miniaturization, dark-field illumination is used, whereby light scattering from the tissue is exploited to homogenize the sensitivity field.https://www.mdpi.com/2304-6732/9/12/907blood vessels imaginghandheld optoacoustic probereal-time imagingunfocused ultrasound transducerwide field of view
spellingShingle Zohar Or
Ahiad R. Levi
Yoav Hazan
Amir Rosenthal
Hand-Held Optoacoustic System for the Localization of Mid-Depth Blood Vessels
Photonics
blood vessels imaging
handheld optoacoustic probe
real-time imaging
unfocused ultrasound transducer
wide field of view
title Hand-Held Optoacoustic System for the Localization of Mid-Depth Blood Vessels
title_full Hand-Held Optoacoustic System for the Localization of Mid-Depth Blood Vessels
title_fullStr Hand-Held Optoacoustic System for the Localization of Mid-Depth Blood Vessels
title_full_unstemmed Hand-Held Optoacoustic System for the Localization of Mid-Depth Blood Vessels
title_short Hand-Held Optoacoustic System for the Localization of Mid-Depth Blood Vessels
title_sort hand held optoacoustic system for the localization of mid depth blood vessels
topic blood vessels imaging
handheld optoacoustic probe
real-time imaging
unfocused ultrasound transducer
wide field of view
url https://www.mdpi.com/2304-6732/9/12/907
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AT ahiadrlevi handheldoptoacousticsystemforthelocalizationofmiddepthbloodvessels
AT yoavhazan handheldoptoacousticsystemforthelocalizationofmiddepthbloodvessels
AT amirrosenthal handheldoptoacousticsystemforthelocalizationofmiddepthbloodvessels