Absorbed dose uncertainty estimation for proton therapy
Successful radiotherapy treatment depends on the absorbed dose evaluation and the possibility to define metrological characteristics of the therapy beam. Radiotherapy requires tumor dose delivery with expanded uncertainty less than ±5 %. It is particularly important to reduce uncertainty during t...
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| Format: | Article |
| Language: | English |
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VINCA Institute of Nuclear Sciences
2012-01-01
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| Series: | Nuclear Technology and Radiation Protection |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/1451-3994/2012/1451-39941203297S.pdf |
| _version_ | 1811343053458243584 |
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| author | Spasić-Jokić Vesna Dobrosavljević Aleksandar Beličev Petar |
| author_facet | Spasić-Jokić Vesna Dobrosavljević Aleksandar Beličev Petar |
| author_sort | Spasić-Jokić Vesna |
| collection | DOAJ |
| description | Successful radiotherapy treatment depends on the absorbed dose evaluation and the possibility to define metrological characteristics of the therapy beam. Radiotherapy requires tumor dose delivery with expanded uncertainty less than ±5 %. It is particularly important to reduce uncertainty during therapy beam calibration as well as to apply all necessary ionization chamber correction factors. Absorbed dose to water was determined using ionometric method. Calibration was performed in reference cobalt beam. Combined standard uncertainty of the calculated absorbed dose to water in 65 MeV proton beam was ±1.97% while the obtained expanded uncertainty of absorbed dose for the same beam quality was ±5.02%. The uncertainty estimation method has been developed within the project TESLA. |
| first_indexed | 2024-04-13T19:21:51Z |
| format | Article |
| id | doaj.art-eb6c2c756baf4f8da217903439d292f0 |
| institution | Directory Open Access Journal |
| issn | 1451-3994 |
| language | English |
| last_indexed | 2024-04-13T19:21:51Z |
| publishDate | 2012-01-01 |
| publisher | VINCA Institute of Nuclear Sciences |
| record_format | Article |
| series | Nuclear Technology and Radiation Protection |
| spelling | doaj.art-eb6c2c756baf4f8da217903439d292f02022-12-22T02:33:30ZengVINCA Institute of Nuclear SciencesNuclear Technology and Radiation Protection1451-39942012-01-0127329730410.2298/NTRP1203297SAbsorbed dose uncertainty estimation for proton therapySpasić-Jokić VesnaDobrosavljević AleksandarBeličev PetarSuccessful radiotherapy treatment depends on the absorbed dose evaluation and the possibility to define metrological characteristics of the therapy beam. Radiotherapy requires tumor dose delivery with expanded uncertainty less than ±5 %. It is particularly important to reduce uncertainty during therapy beam calibration as well as to apply all necessary ionization chamber correction factors. Absorbed dose to water was determined using ionometric method. Calibration was performed in reference cobalt beam. Combined standard uncertainty of the calculated absorbed dose to water in 65 MeV proton beam was ±1.97% while the obtained expanded uncertainty of absorbed dose for the same beam quality was ±5.02%. The uncertainty estimation method has been developed within the project TESLA.http://www.doiserbia.nb.rs/img/doi/1451-3994/2012/1451-39941203297S.pdfprotonsabsorbed dosetherapyuncertainty |
| spellingShingle | Spasić-Jokić Vesna Dobrosavljević Aleksandar Beličev Petar Absorbed dose uncertainty estimation for proton therapy Nuclear Technology and Radiation Protection protons absorbed dose therapy uncertainty |
| title | Absorbed dose uncertainty estimation for proton therapy |
| title_full | Absorbed dose uncertainty estimation for proton therapy |
| title_fullStr | Absorbed dose uncertainty estimation for proton therapy |
| title_full_unstemmed | Absorbed dose uncertainty estimation for proton therapy |
| title_short | Absorbed dose uncertainty estimation for proton therapy |
| title_sort | absorbed dose uncertainty estimation for proton therapy |
| topic | protons absorbed dose therapy uncertainty |
| url | http://www.doiserbia.nb.rs/img/doi/1451-3994/2012/1451-39941203297S.pdf |
| work_keys_str_mv | AT spasicjokicvesna absorbeddoseuncertaintyestimationforprotontherapy AT dobrosavljevicaleksandar absorbeddoseuncertaintyestimationforprotontherapy AT belicevpetar absorbeddoseuncertaintyestimationforprotontherapy |