Tirofiban, a Glycoprotein IIb/IIIa Antagonist, Has a Protective Effect on Decompression Sickness in Rats: Is the Crosstalk Between Platelet and Leukocytes Essential?

Tirofiban, a Glycoprotein IIb/IIIa Antagonist, Has a Protective Effect on Decompression Sickness in Rats: Is the Crosstalk Between Platelet and Leukocytes Essential?

In its severest forms, decompression sickness (DCS) may extend systemically and/or induce severe neurological deficits, including paralysis or even death. It seems that the sterile and ischemic inflammatory phenomena are consecutive to the reaction of the bubbles with the organism and that the blood...

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Bibliographic Details
Main Authors: Kate Lambrechts, Sébastien de Maistre, Jacques H. Abraini, Jean-Eric Blatteau, Jean-Jacques Risso, Nicolas Vallée
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Physiology
Subjects:
dive
ischemia
systemic inflammation
pressure
stroke
inert gas
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.00906/full

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