MR-LINAC, a New Partner in Radiation Oncology: Current Landscape
Technological advances in radiation oncology are oriented towards improving treatment precision and tumor control. Among these advances, magnetic-resonance-image-guided radiation therapy (MRgRT) stands out, with technological advances to deliver targeted treatments adapted to a tumor’s anatomy on th...
| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-01-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/16/2/270 |
| _version_ | 1797344519568490496 |
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| author | Abrahams Ocanto Lisselott Torres Miguel Montijano Diego Rincón Castalia Fernández Beatriz Sevilla Daniela Gonsalves Macarena Teja Marcos Guijarro Luis Glaría Raúl Hernánz Juan Zafra-Martin Noelia Sanmamed Amar Kishan Filippo Alongi Drew Moghanaki Himanshu Nagar Felipe Couñago |
| author_facet | Abrahams Ocanto Lisselott Torres Miguel Montijano Diego Rincón Castalia Fernández Beatriz Sevilla Daniela Gonsalves Macarena Teja Marcos Guijarro Luis Glaría Raúl Hernánz Juan Zafra-Martin Noelia Sanmamed Amar Kishan Filippo Alongi Drew Moghanaki Himanshu Nagar Felipe Couñago |
| author_sort | Abrahams Ocanto |
| collection | DOAJ |
| description | Technological advances in radiation oncology are oriented towards improving treatment precision and tumor control. Among these advances, magnetic-resonance-image-guided radiation therapy (MRgRT) stands out, with technological advances to deliver targeted treatments adapted to a tumor’s anatomy on the day while minimizing incidental exposure to organs at risk, offering an unprecedented therapeutic advantage compared to X-ray-based IGRT delivery systems. This new technology changes the traditional workflow in radiation oncology and requires an evolution in team coordination to administer more precise treatments. Once implemented, it paves the way for newer indication for radiation therapy to safely deliver higher doses than ever before, with better preservation of healthy tissues to optimize patient outcomes. In this narrative review, we assess the technical aspects of the novel linear accelerators that can deliver MRgRT and summarize the available published experience to date, focusing on oncological results and future challenges. |
| first_indexed | 2024-03-08T11:03:47Z |
| format | Article |
| id | doaj.art-eb726595ccd44685b4ff5d0700f0c0a0 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-08T11:03:47Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-eb726595ccd44685b4ff5d0700f0c0a02024-01-26T15:34:38ZengMDPI AGCancers2072-66942024-01-0116227010.3390/cancers16020270MR-LINAC, a New Partner in Radiation Oncology: Current LandscapeAbrahams Ocanto0Lisselott Torres1Miguel Montijano2Diego Rincón3Castalia Fernández4Beatriz Sevilla5Daniela Gonsalves6Macarena Teja7Marcos Guijarro8Luis Glaría9Raúl Hernánz10Juan Zafra-Martin11Noelia Sanmamed12Amar Kishan13Filippo Alongi14Drew Moghanaki15Himanshu Nagar16Felipe Couñago17Department of Radiation Oncology, Hospital Universitario San Francisco de Asís, GenesisCare, 28002 Madrid, SpainDepartment of Radiation Oncology, Hospital Universitario San Francisco de Asís, GenesisCare, 28002 Madrid, SpainDepartment of Radiation Oncology, Hospital Universitario San Francisco de Asís, GenesisCare, 28002 Madrid, SpainDepartment of Radiation Oncology, Hospital Universitario San Francisco de Asís, GenesisCare, 28002 Madrid, SpainDepartment of Radiation Oncology, Hospital Universitario San Francisco de Asís, GenesisCare, 28002 Madrid, SpainDepartment of Radiation Oncology, Hospital Universitario San Francisco de Asís, GenesisCare, 28002 Madrid, SpainDepartment of Radiation Oncology, Hospital Universitario San Francisco de Asís, GenesisCare, 28002 Madrid, SpainDepartment of Radiation Oncology, Hospital Universitario San Francisco de Asís, GenesisCare, 28002 Madrid, SpainDepartment of Radiation Oncology, Hospital Universitario San Francisco de Asís, GenesisCare, 28002 Madrid, SpainDepartment of Radiation Oncology, Hospital Universitario San Francisco de Asís, GenesisCare, 28002 Madrid, SpainDepartment of Radiation Oncology, Hospital Universitario San Francisco de Asís, GenesisCare, 28002 Madrid, SpainGroup of Translational Research in Cancer Immunotherapy, Centro de Investigaciones Médico-Sanitarias (CIMES), Instituto de Investigación Biomédica de Málaga (IBIMA), Universidad de Málaga (UMA), 29010 Málaga, SpainDepartment of Radiation Oncology, Hospital Universitario Clínico San Carlos, 28040 Madrid, SpainDepartment of Radiation Oncology, University of California, Los Angeles, CA 90095, USAAdvanced Radiation Oncology Department, Cancer Care Center, IRCCS Sacro Cuore Don Calabria Hospital, 37024 Negrar, ItalyUCLA Department of Radiation Oncology, University of California Los Angeles, Los Angeles, CA 90095, USADepartment of Radiation Oncology, Weill Cornell Medicine, New York, NY 10065, USADepartment of Radiation Oncology, Hospital Universitario San Francisco de Asís, GenesisCare, 28002 Madrid, SpainTechnological advances in radiation oncology are oriented towards improving treatment precision and tumor control. Among these advances, magnetic-resonance-image-guided radiation therapy (MRgRT) stands out, with technological advances to deliver targeted treatments adapted to a tumor’s anatomy on the day while minimizing incidental exposure to organs at risk, offering an unprecedented therapeutic advantage compared to X-ray-based IGRT delivery systems. This new technology changes the traditional workflow in radiation oncology and requires an evolution in team coordination to administer more precise treatments. Once implemented, it paves the way for newer indication for radiation therapy to safely deliver higher doses than ever before, with better preservation of healthy tissues to optimize patient outcomes. In this narrative review, we assess the technical aspects of the novel linear accelerators that can deliver MRgRT and summarize the available published experience to date, focusing on oncological results and future challenges.https://www.mdpi.com/2072-6694/16/2/270adaptative radiotherapyimage guidancestereotactic body radiotherapyradiotherapy |
| spellingShingle | Abrahams Ocanto Lisselott Torres Miguel Montijano Diego Rincón Castalia Fernández Beatriz Sevilla Daniela Gonsalves Macarena Teja Marcos Guijarro Luis Glaría Raúl Hernánz Juan Zafra-Martin Noelia Sanmamed Amar Kishan Filippo Alongi Drew Moghanaki Himanshu Nagar Felipe Couñago MR-LINAC, a New Partner in Radiation Oncology: Current Landscape Cancers adaptative radiotherapy image guidance stereotactic body radiotherapy radiotherapy |
| title | MR-LINAC, a New Partner in Radiation Oncology: Current Landscape |
| title_full | MR-LINAC, a New Partner in Radiation Oncology: Current Landscape |
| title_fullStr | MR-LINAC, a New Partner in Radiation Oncology: Current Landscape |
| title_full_unstemmed | MR-LINAC, a New Partner in Radiation Oncology: Current Landscape |
| title_short | MR-LINAC, a New Partner in Radiation Oncology: Current Landscape |
| title_sort | mr linac a new partner in radiation oncology current landscape |
| topic | adaptative radiotherapy image guidance stereotactic body radiotherapy radiotherapy |
| url | https://www.mdpi.com/2072-6694/16/2/270 |
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