Synthesis, effect of substituents on the regiochemistry and equilibrium studies of tetrazolo[1,5-a]pyrimidine/2-azidopyrimidines

Synthesis, effect of substituents on the regiochemistry and equilibrium studies of tetrazolo[1,5-a]pyrimidine/2-azidopyrimidines

An efficient synthesis methodology for a series of tetrazolo[1,5-a]pyrimidines substituted at the 5- and 7-positions from the cyclocondensation reaction [CCC + NCN] was developed. The NCN corresponds to 5-aminotetrazole and CCC to β-enaminone. Two distinct products were observed in accordance with t...

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Bibliographic Details
Main Authors: Elisandra Scapin, Paulo R. S. Salbego, Caroline R. Bender, Alexandre R. Meyer, Anderson B. Pagliari, Tainára Orlando, Geórgia C. Zimmer, Clarissa P. Frizzo, Helio G. Bonacorso, Nilo Zanatta, Marcos A. P. Martins
Format: Article
Language:English
Published: Beilstein-Institut 2017-11-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
5-aminotetrazol
azide–tetrazole equilibrium
2-azidopyrimidine
β-enaminones
tetrazolo[1,5-a]pyrimidine
trifluoromethylatedtetrazolo[1,5-a]pyrimidines
Online Access:https://doi.org/10.3762/bjoc.13.237

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