Regulation of Aldo-keto Reductases in Human Diseases

Regulation of Aldo-keto Reductases in Human Diseases

The aldo-keto reductases (AKRs) are a superfamily of NAD(P)H-linked oxidoreductases, which reduce aldehydes and ketones to their respective primary and secondary alcohols. AKR enzymes are increasingly being recognized to play an important role in the transformation and detoxification of aldehydes an...

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Bibliographic Details
Main Authors:	Wei-Dong eChen, Yanqiao eZhang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2012-03-01
Series:	Frontiers in Pharmacology
Subjects:	regulation transcription factor Human Disease aldo-keto reductase response element
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00035/full

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