Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation

Protective roles of MITOL against myocardial senescence and ischemic injury partly via Drp1 regulation

Summary: Abnormal mitochondrial fragmentation by dynamin-related protein1 (Drp1) is associated with the progression of aging-associated heart diseases, including heart failure and myocardial infarction (MI). Here, we report a protective role of outer mitochondrial membrane (OMM)-localized E3 ubiquit...

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Bibliographic Details
Main Authors: Takeshi Tokuyama, Hideki Uosaki, Ayumu Sugiura, Gen Nishitai, Keisuke Takeda, Shun Nagashima, Isshin Shiiba, Naoki Ito, Taku Amo, Satoshi Mohri, Akiyuki Nishimura, Motohiro Nishida, Ayumu Konno, Hirokazu Hirai, Satoshi Ishido, Takahiro Yoshizawa, Takayuki Shindo, Shingo Takada, Shintaro Kinugawa, Ryoko Inatome, Shigeru Yanagi
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:iScience
Subjects:
Physiology
Cellular physiology
Molecular biology
Developmental biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222008549

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http://www.sciencedirect.com/science/article/pii/S2589004222008549

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