miRNAs in Lung Development and Diseases
The development of the lung involves a diverse group of molecules that regulate cellular processes, organ formation, and maturation. The various stages of lung development are marked by accumulation of small RNAs that promote or repress underlying mechanisms, depending on the physiological environme...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-04-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/21/8/2765 |
| _version_ | 1797570585753026560 |
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| author | Eistine Boateng Susanne Krauss-Etschmann |
| author_facet | Eistine Boateng Susanne Krauss-Etschmann |
| author_sort | Eistine Boateng |
| collection | DOAJ |
| description | The development of the lung involves a diverse group of molecules that regulate cellular processes, organ formation, and maturation. The various stages of lung development are marked by accumulation of small RNAs that promote or repress underlying mechanisms, depending on the physiological environment <i>in utero</i> and postnatally. To some extent, the pathogenesis of various lung diseases is regulated by small RNAs. In this review, we discussed miRNAs regulation of lung development and diseases, that is, COPD, asthma, pulmonary fibrosis, and pulmonary arterial hypertension, and also highlighted possible connotations for human lung health. |
| first_indexed | 2024-03-10T20:26:37Z |
| format | Article |
| id | doaj.art-eb7b3156394d46a38f51f343af03d202 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T20:26:37Z |
| publishDate | 2020-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-eb7b3156394d46a38f51f343af03d2022023-11-19T21:46:20ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672020-04-01218276510.3390/ijms21082765miRNAs in Lung Development and DiseasesEistine Boateng0Susanne Krauss-Etschmann1Early Life Origins of Chronic Lung Diseases, Research Center Borstel, Leibniz Lung Center, Member of the German Center for Lung Research (DZL), 23845 Borstel, GermanyEarly Life Origins of Chronic Lung Diseases, Research Center Borstel, Leibniz Lung Center, Member of the German Center for Lung Research (DZL), 23845 Borstel, GermanyThe development of the lung involves a diverse group of molecules that regulate cellular processes, organ formation, and maturation. The various stages of lung development are marked by accumulation of small RNAs that promote or repress underlying mechanisms, depending on the physiological environment <i>in utero</i> and postnatally. To some extent, the pathogenesis of various lung diseases is regulated by small RNAs. In this review, we discussed miRNAs regulation of lung development and diseases, that is, COPD, asthma, pulmonary fibrosis, and pulmonary arterial hypertension, and also highlighted possible connotations for human lung health.https://www.mdpi.com/1422-0067/21/8/2765lung developmentlung diseasesmiRNAhumanmouse |
| spellingShingle | Eistine Boateng Susanne Krauss-Etschmann miRNAs in Lung Development and Diseases International Journal of Molecular Sciences lung development lung diseases miRNA human mouse |
| title | miRNAs in Lung Development and Diseases |
| title_full | miRNAs in Lung Development and Diseases |
| title_fullStr | miRNAs in Lung Development and Diseases |
| title_full_unstemmed | miRNAs in Lung Development and Diseases |
| title_short | miRNAs in Lung Development and Diseases |
| title_sort | mirnas in lung development and diseases |
| topic | lung development lung diseases miRNA human mouse |
| url | https://www.mdpi.com/1422-0067/21/8/2765 |
| work_keys_str_mv | AT eistineboateng mirnasinlungdevelopmentanddiseases AT susannekraussetschmann mirnasinlungdevelopmentanddiseases |