Checkpoint inhibition of origin firing prevents inappropriate replication outside of S-phase
Checkpoints maintain the order of cell cycle events during DNA damage or incomplete replication. How the checkpoint response is tailored to different phases of the cell cycle remains poorly understood. The S-phase checkpoint for example results in the slowing of replication, which in budding yeast o...
Main Authors: | Mark C Johnson, Geylani Can, Miguel Monteiro Santos, Diana Alexander, Philip Zegerman |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-01-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/63589 |
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