Tissue-Nonspecific Alkaline Phosphatase in Central Nervous System Health and Disease: A Focus on Brain Microvascular Endothelial Cells

Tissue-Nonspecific Alkaline Phosphatase in Central Nervous System Health and Disease: A Focus on Brain Microvascular Endothelial Cells

Tissue-nonspecific alkaline phosphatase (TNAP) is an ectoenzyme bound to the plasma membranes of numerous cells via a glycosylphosphatidylinositol (GPI) moiety. TNAP’s function is well-recognized from earlier studies establishing its important role in bone mineralization. TNAP is also highly express...

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Bibliographic Details
Main Authors:	Divine C. Nwafor, Allison L. Brichacek, Ahsan Ali, Candice M. Brown
Format:	Article
Language:	English
Published:	MDPI AG 2021-05-01
Series:	International Journal of Molecular Sciences
Subjects:	brain microvascular endothelial cells cerebral microvessels tissue-nonspecific alkaline phosphatase <i>Alpl</i> TNAP blood-brain barrier
Online Access:	https://www.mdpi.com/1422-0067/22/10/5257

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