Overweight and Obesity are Risk Factors for Coronavirus Disease 2019: A Propensity Score-Matched Case-Control Study
Although obesity is a risk factor for infection, whether it has the same effect on coronavirus disease 2019 (COVID-19) need confirming. We conducted a retrospective propensity score matched case-control study to examine the association between obesity and COVID-19. This study included data from the...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Korean Endocrine Society
2021-02-01
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| Series: | Endocrinology and Metabolism |
| Subjects: | |
| Online Access: | http://www.e-enm.org/upload/pdf/enm-2020-856.pdf |
| _version_ | 1811331308904775680 |
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| author | Wonjun Ji Rugyeom Lee Kyungmin Huh Minsun Kang In Cheol Hwang Munkhzul Radnaabaatar Dae Ho Lee Jaehun Jung |
| author_facet | Wonjun Ji Rugyeom Lee Kyungmin Huh Minsun Kang In Cheol Hwang Munkhzul Radnaabaatar Dae Ho Lee Jaehun Jung |
| author_sort | Wonjun Ji |
| collection | DOAJ |
| description | Although obesity is a risk factor for infection, whether it has the same effect on coronavirus disease 2019 (COVID-19) need confirming. We conducted a retrospective propensity score matched case-control study to examine the association between obesity and COVID-19. This study included data from the Nationwide COVID-19 Registry and the Biennial Health Checkup database, until May 30, 2020. We identified 2,231 patients with confirmed COVID-19 and 10-fold-matched negative test controls. Overweight (body mass index [BMI] 23 to 24.9 kg/m2; adjusted odds ratio [aOR], 1.16; 95% confidence interval [CI], 1.1.03 to 1.30) and class 1 obesity (BMI 25 to 29.9 kg/m2; aOR, 1.27; 95% CI, 1.14 to 1.42) had significantly increased COVID-19 risk, while classes 2 and 3 obesity (BMI ≥30 kg/m2) showed similar but non-significant trend. Females and those <50 years had more robust association pattern. Overweight and obesity are possible risk factors of COVID-19. |
| first_indexed | 2024-04-13T16:18:37Z |
| format | Article |
| id | doaj.art-eb86be064be143b69785bc00656a9c1d |
| institution | Directory Open Access Journal |
| issn | 2093-596X 2093-5978 |
| language | English |
| last_indexed | 2024-04-13T16:18:37Z |
| publishDate | 2021-02-01 |
| publisher | Korean Endocrine Society |
| record_format | Article |
| series | Endocrinology and Metabolism |
| spelling | doaj.art-eb86be064be143b69785bc00656a9c1d2022-12-22T02:40:00ZengKorean Endocrine SocietyEndocrinology and Metabolism2093-596X2093-59782021-02-0136119620010.3803/EnM.2020.8562134Overweight and Obesity are Risk Factors for Coronavirus Disease 2019: A Propensity Score-Matched Case-Control StudyWonjun Ji0Rugyeom Lee1Kyungmin Huh2Minsun Kang3In Cheol Hwang4Munkhzul Radnaabaatar5Dae Ho Lee6Jaehun Jung7 Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Artificial Intelligence and Big-Data Convergence Center, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Korea Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea Artificial Intelligence and Big-Data Convergence Center, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Korea Department of Family Medicine, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Korea Artificial Intelligence and Big-Data Convergence Center, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Korea Department of Internal Medicine, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, Korea Artificial Intelligence and Big-Data Convergence Center, Gachon University Gil Medical Center, Gachon University College of Medicine, Incheon, KoreaAlthough obesity is a risk factor for infection, whether it has the same effect on coronavirus disease 2019 (COVID-19) need confirming. We conducted a retrospective propensity score matched case-control study to examine the association between obesity and COVID-19. This study included data from the Nationwide COVID-19 Registry and the Biennial Health Checkup database, until May 30, 2020. We identified 2,231 patients with confirmed COVID-19 and 10-fold-matched negative test controls. Overweight (body mass index [BMI] 23 to 24.9 kg/m2; adjusted odds ratio [aOR], 1.16; 95% confidence interval [CI], 1.1.03 to 1.30) and class 1 obesity (BMI 25 to 29.9 kg/m2; aOR, 1.27; 95% CI, 1.14 to 1.42) had significantly increased COVID-19 risk, while classes 2 and 3 obesity (BMI ≥30 kg/m2) showed similar but non-significant trend. Females and those <50 years had more robust association pattern. Overweight and obesity are possible risk factors of COVID-19.http://www.e-enm.org/upload/pdf/enm-2020-856.pdfcovid-19obesityoverweightinfections |
| spellingShingle | Wonjun Ji Rugyeom Lee Kyungmin Huh Minsun Kang In Cheol Hwang Munkhzul Radnaabaatar Dae Ho Lee Jaehun Jung Overweight and Obesity are Risk Factors for Coronavirus Disease 2019: A Propensity Score-Matched Case-Control Study Endocrinology and Metabolism covid-19 obesity overweight infections |
| title | Overweight and Obesity are Risk Factors for Coronavirus Disease 2019: A Propensity Score-Matched Case-Control Study |
| title_full | Overweight and Obesity are Risk Factors for Coronavirus Disease 2019: A Propensity Score-Matched Case-Control Study |
| title_fullStr | Overweight and Obesity are Risk Factors for Coronavirus Disease 2019: A Propensity Score-Matched Case-Control Study |
| title_full_unstemmed | Overweight and Obesity are Risk Factors for Coronavirus Disease 2019: A Propensity Score-Matched Case-Control Study |
| title_short | Overweight and Obesity are Risk Factors for Coronavirus Disease 2019: A Propensity Score-Matched Case-Control Study |
| title_sort | overweight and obesity are risk factors for coronavirus disease 2019 a propensity score matched case control study |
| topic | covid-19 obesity overweight infections |
| url | http://www.e-enm.org/upload/pdf/enm-2020-856.pdf |
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