Asymptomatic moyamoya syndrome, atlantoaxial subluxation and basal ganglia calcification in a child with Down syndrome
Down syndrome, the most common chromosomal abnormality, may be associated with various neurologic complications such as moyamoya syndrome, cervical spinal cord compression due to atlantoaxial subluxation, and basal ganglia damage, as well as epileptic seizures and stroke. Many cases of Down syndrome...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Korean Pediatric Society
2013-12-01
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| Series: | Korean Journal of Pediatrics |
| Subjects: | |
| Online Access: | http://kjp.or.kr/upload/pdf/kjped-56-540.pdf |
| _version_ | 1830286813954048000 |
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| author | Kyung Yeon Lee Kun-Soo Lee Young Cheol Weon |
| author_facet | Kyung Yeon Lee Kun-Soo Lee Young Cheol Weon |
| author_sort | Kyung Yeon Lee |
| collection | DOAJ |
| description | Down syndrome, the most common chromosomal abnormality, may be associated with various neurologic complications such as moyamoya syndrome, cervical spinal cord compression due to atlantoaxial subluxation, and basal ganglia damage, as well as epileptic seizures and stroke. Many cases of Down syndrome accompanied by isolated neurologic manifestations have been reported in children; however, Down syndrome with multiple neurologic conditions is rare. Here, we have reported a case of Down syndrome in a 10-year-old girl who presented with asymptomatic moyamoya syndrome, atlantoaxial subluxation with spinal cord compression, and basal ganglia calcification. To the best of our knowledge, this is the first report of Down syndrome, in a child, which was accompanied by these 3 neurologic complications simultaneously. As seen in this case, patients with Down syndrome may have neurologic conditions without any obvious neurologic symptoms; hence, patients with Down syndrome should be carefully examined for the presence of neurologic conditions. |
| first_indexed | 2024-12-19T04:06:22Z |
| format | Article |
| id | doaj.art-eb8bf53b51a54ffb801b902744cfdd1f |
| institution | Directory Open Access Journal |
| issn | 1738-1061 2092-7258 |
| language | English |
| last_indexed | 2024-12-19T04:06:22Z |
| publishDate | 2013-12-01 |
| publisher | Korean Pediatric Society |
| record_format | Article |
| series | Korean Journal of Pediatrics |
| spelling | doaj.art-eb8bf53b51a54ffb801b902744cfdd1f2022-12-21T20:36:32ZengKorean Pediatric SocietyKorean Journal of Pediatrics1738-10612092-72582013-12-01561254054310.3345/kjp.2013.56.12.5402013600023Asymptomatic moyamoya syndrome, atlantoaxial subluxation and basal ganglia calcification in a child with Down syndromeKyung Yeon Lee0Kun-Soo Lee1Young Cheol Weon2Department of Pediatrics, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.Department of Neurosurgery, Inje University Busan Paik Hospital, Busan, Korea.Department of Radiology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.Down syndrome, the most common chromosomal abnormality, may be associated with various neurologic complications such as moyamoya syndrome, cervical spinal cord compression due to atlantoaxial subluxation, and basal ganglia damage, as well as epileptic seizures and stroke. Many cases of Down syndrome accompanied by isolated neurologic manifestations have been reported in children; however, Down syndrome with multiple neurologic conditions is rare. Here, we have reported a case of Down syndrome in a 10-year-old girl who presented with asymptomatic moyamoya syndrome, atlantoaxial subluxation with spinal cord compression, and basal ganglia calcification. To the best of our knowledge, this is the first report of Down syndrome, in a child, which was accompanied by these 3 neurologic complications simultaneously. As seen in this case, patients with Down syndrome may have neurologic conditions without any obvious neurologic symptoms; hence, patients with Down syndrome should be carefully examined for the presence of neurologic conditions.http://kjp.or.kr/upload/pdf/kjped-56-540.pdfDown syndromeMoyamoya diseaseAtlantoaxial instabilityBasal ganglia calcification |
| spellingShingle | Kyung Yeon Lee Kun-Soo Lee Young Cheol Weon Asymptomatic moyamoya syndrome, atlantoaxial subluxation and basal ganglia calcification in a child with Down syndrome Korean Journal of Pediatrics Down syndrome Moyamoya disease Atlantoaxial instability Basal ganglia calcification |
| title | Asymptomatic moyamoya syndrome, atlantoaxial subluxation and basal ganglia calcification in a child with Down syndrome |
| title_full | Asymptomatic moyamoya syndrome, atlantoaxial subluxation and basal ganglia calcification in a child with Down syndrome |
| title_fullStr | Asymptomatic moyamoya syndrome, atlantoaxial subluxation and basal ganglia calcification in a child with Down syndrome |
| title_full_unstemmed | Asymptomatic moyamoya syndrome, atlantoaxial subluxation and basal ganglia calcification in a child with Down syndrome |
| title_short | Asymptomatic moyamoya syndrome, atlantoaxial subluxation and basal ganglia calcification in a child with Down syndrome |
| title_sort | asymptomatic moyamoya syndrome atlantoaxial subluxation and basal ganglia calcification in a child with down syndrome |
| topic | Down syndrome Moyamoya disease Atlantoaxial instability Basal ganglia calcification |
| url | http://kjp.or.kr/upload/pdf/kjped-56-540.pdf |
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