Ang1 and Ang4 differentially affect colitis and carcinogenesis in an AOM-DSS mouse model.

<h4>Introduction</h4>Angiogenin-1 (Ang1) and angiogenin-4 (Ang4) are 14-kDa ribonucleases with potent angiogenic and antimicrobial properties. The role of Ang1 and Ang4 in chronic colitis and colitis-associated cancer has not been previously studied.<h4>Methods</h4>Wild-type...

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Bibliographic Details
Main Authors: Alexander Hu, Cullen Roberts, Andrei Moscalu, Mark Redston, James Yoo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0281529