Retrospective Cohort Study of Caveolin-1 Expression as Prognostic Factor in Unresectable Locally Advanced or Metastatic Pancreatic Cancer Patients

Retrospective Cohort Study of Caveolin-1 Expression as Prognostic Factor in Unresectable Locally Advanced or Metastatic Pancreatic Cancer Patients

Caveolin-1 (Cav-1) plays a key role in various neoplastic diseases and is upregulated in different cancers, including pancreatic ductal adenocarcinoma (PDAC). Furthermore, Cav-1 is critical for the uptake of albumin as well as nab-paclitaxel in PDAC cells. Here, we investigated the prognostic impact...

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Bibliographic Details
Main Authors: Alessandro Bittoni, Riccardo Giampieri, Federica Pecci, Giada Pinterpe, Alessandra Mandolesi, Michela Del Prete, Antonio Zizzi, Sonia Crocetti, Carolina Liguori, Giulia Mentrasti, Luca Cantini, Chiara Pellei, Renato Bisonni, Marina Scarpelli, Rossana Berardi
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Current Oncology
Subjects:
Caveolin-1
pancreatic cancer
1st line chemotherapy
prognosis
Online Access:https://www.mdpi.com/1718-7729/28/5/303

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