Role of IL6 -174 G/C, IL10 1082G/A and IL10 -592C/A in the pathogenesis of keratoconus and development of recurrent erosion in Ukrainian patients with lattice corneal dystrophy

Role of IL6 -174 G/C, IL10 1082G/A and IL10 -592C/A in the pathogenesis of keratoconus and development of recurrent erosion in Ukrainian patients with lattice corneal dystrophy

Background: Keratoconus (KC, or corneal ectasia) is a multifactorial disease with a genetic component and an average annual incidence rate of 2.0/100,000 persons. Lattice corneal stromal dystrophy (LCD), a monogenic disorder with varying phenotypic manifestations, is the most common hereditary corne...

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Bibliographic Details
Main Authors: Livshits L.A., Drozhzhyna G.I., Kucherenko A.M., Ivanovska O.V., Gaidamaka T.B., Gorodna O.V., Sereda K.V.
Format: Article
Language:English
Published: Ukrainian Society of Ophthalmologists 2020-04-01
Series:Journal of Ophthalmology
Subjects:
keratoconus
lattice corneal dystrophy
recurrent erosions
clinical phenotype
interleukin gene polymorphism
genetic predisposition
Online Access:https://www.ozhurnal.com/en/archive/2020/2/1-fulltext

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