Understanding the Role of HLA Class I Molecules in the Immune Response to Influenza Infection and Rational Design of a Peptide-Based Vaccine

Understanding the Role of HLA Class I Molecules in the Immune Response to Influenza Infection and Rational Design of a Peptide-Based Vaccine

Influenza A virus is a respiratory pathogen that is responsible for regular epidemics and occasional pandemics that result in substantial damage to life and the economy. The yearly reformulation of trivalent or quadrivalent flu vaccines encompassing surface glycoproteins derived from the current cir...

Full description

Bibliographic Details
Main Authors:	A. K. M. Muraduzzaman, Patricia T. Illing, Nicole A. Mifsud, Anthony W. Purcell
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Series:	Viruses
Subjects:	influenza HLA vaccine
Online Access:	https://www.mdpi.com/1999-4915/14/11/2578

Similar Items

Downregulation of MHC Class I Expression by Influenza A and B Viruses
by: Marios Koutsakos, et al.
Published: (2019-05-01)

HLA class Ib molecules and immune cells in pregnancy and preeclampsia
by: Snezana eDjurisic, et al.
Published: (2014-12-01)

possible association of HLA class-1 molecules with rheumatoid arthritis in Iraqi patients
by: batool A. Al-Haidary, et al.
Published: (2005-10-01)

Divergent Peptide Presentations of HLA-A*30 Alleles Revealed by Structures With Pathogen Peptides
by: Shiyan Zhu, et al.
Published: (2019-07-01)

Possible association between class- HLA molecules & idiopathic nephrotic syndrome
by: Batool A. Al-Haidary, et al.
Published: (2007-10-01)

HLA-associated protection of lymphocytes during influenza virus infection
by: Eliana E. Ochoa, et al.
Published: (2020-08-01)

Homologous peptides derived from influenza A, B and C viruses induce variable CD8+ T cell responses with cross‐reactive potential
by: Andrea T Nguyen, et al.
Published: (2022-01-01)

Diversity in the HLA-I Recognition of HLA-F Monoclonal Antibodies: HLA-F or HLA-Ib Monospecific, HLA-E or HLA-G Bispecific Antibodies with or without HLA-Ia Reactivity
by: Mepur H. Ravindranath, et al.
Published: (2024-01-01)

Possible association of HLA class-I Molecules with autoimmune Hepatitis in Iraqi patients
by: Eman Sh. AL-Obeidy, et al.
Published: (2009-04-01)

HLA class-1 molecules in Iraqi patients with rheumatoid arthritis . A sporadic & familial study
by: batool A. Al-Haidary, et al.
Published: (2006-01-01)

Histological Characterization of Class I HLA Molecules in Whole Umbilical Cord Tissue Towards an Inexhaustible Graft Alternative for Reconstructive Surgery
by: Yue Ying Yao, et al.
Published: (2023-01-01)

The Association of HLA Class 1 and Class 2 Antigens with Multiple Myeloma in Iranian Patients
by: Arezou Sayad, et al.
Published: (2014-12-01)

Expression of the Non-classical HLA-E, -F, -G Molecules in the Tumour Microenvironment
by: Ormandjieva Anastasia
Published: (2023-08-01)

Bioinformatics analysis identifies a key gene HLA_DPA1 in severe influenza-associated immune infiltration
by: Liang Chen, et al.
Published: (2024-03-01)

possible association of HLA class-1 molecules with colorectal cancer in Iraqi patients
by: batool H. AL-Ghurabi, et al.
Published: (2006-04-01)

Set Theory Applied to the Mathematical Characterization of HLA Class II Binding Peptides
by: Javier Rodríguez Velásquez, MD, esp.1
Published: (2008-04-01)

Structural Modeling and Molecular Dynamics of the Immune Checkpoint Molecule HLA-G
by: Thais Arns, et al.
Published: (2020-11-01)

HLA-DO and its role in MHC Class II antigen presentation
by: Yuri O Poluektov, et al.
Published: (2013-08-01)

Expression pattern of HLA-G and HLA-DR molecules on lymphocytes of women and their children with septal congenital heart defects
by: A. V. Shabaldin, et al.
Published: (2024-01-01)

Fighting flu: novel CD8+ T‐cell targets are required for future influenza vaccines
by: Samuel Liwei Leong, et al.
Published: (2024-01-01)

Susceptibility and Severity of COVID-19 Are Both Associated With Lower Overall Viral–Peptide Binding Repertoire of HLA Class I Molecules, Especially in Younger People
by: Hamid Reza Ghasemi Basir, et al.
Published: (2022-07-01)

Advances in the study of HLA class Ib in maternal-fetal immune tolerance
by: Yiran Yang, et al.
Published: (2022-08-01)

Interrelation of HLA-I and class II major histocompatibility complex molecules with clinical and morphological signs of breast cancer: A retrospective cohort study
by: Svetlana V. Chulkova, et al.
Published: (2023-08-01)

Identification of presented SARS-CoV-2 HLA class I and HLA class II peptides using HLA peptidomics
by: Adi Nagler, et al.
Published: (2021-06-01)

Broad-Based Influenza-Specific CD8<sup>+</sup> T Cell Response without the Typical Immunodominance Hierarchy and Its Potential Implication
by: Miaojuan Huang, et al.
Published: (2021-06-01)

Peptide presentation by HLA-DQ molecules is associated with the development of immune tolerance
by: Máté Manczinger, et al.
Published: (2018-07-01)

Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity
by: Prithvi Raj, et al.
Published: (2016-02-01)

The evaluation of HLA class I association with allergic Asthma
by: E.Alijani (M.Sc), et al.
Published: (2002-09-01)

Estudo de polimorfismos genéticos do HLA (classes I e II) e do TNF-á em doentes com sarcoidose HLA class I and II and TNF-á gene polymorphisms in sarcoidosis patients
by: António Morais, et al.
Published: (2008-12-01)

Analysis of HLA-A, HLA-B and HLA-DRB1 allelic frequencies in tertiary care from Telangana and Andhra Pradesh
by: Radhika Chowdary, et al.
Published: (2014-06-01)

Toxoplasma gondii peptide ligands open the gate of the HLA class I binding groove
by: Curtis McMurtrey, et al.
Published: (2016-01-01)

HLA class II molecule HLA-DRA identifies immuno-hot tumors and predicts the therapeutic response to anti-PD-1 immunotherapy in NSCLC
by: Jie Mei, et al.
Published: (2022-07-01)

SARS-CoV-2 Spike-Derived Peptides Presented by HLA Molecules
by: Andrea T. Nguyen, et al.
Published: (2021-05-01)

HLA-G molecules in autoimmune diseases and infections
by: Roberta eRizzo, et al.
Published: (2014-11-01)

Alterations in SARS-CoV-2 Omicron and Delta peptides presentation by HLA molecules
by: Stepan Nersisyan, et al.
Published: (2022-04-01)

Intrinsic Folding Properties of the HLA-B27 Heavy Chain Revealed by Single Chain Trimer Versions of Peptide-Loaded Class I Major Histocompatibility Complex Molecules
by: Izabela Lenart, et al.
Published: (2022-07-01)

HLA-B and HLA-C Differ in Their Nanoscale Organization at Cell Surfaces
by: Philippa R. Kennedy, et al.
Published: (2019-01-01)

Evaluation of HLA-G immune checkpoint molecule in melanocytic lesions
by: Raylane P Gomes, et al.
Published: (2020-05-01)

Preferential HLA-B27 Allorecognition Displayed by Multiple Cross-Reactive Antiviral CD8+ T Cell Receptors
by: Louise C. Rowntree, et al.
Published: (2020-02-01)

HLA class-I-peptide stability mediates CD8+ T cell immunodominance hierarchies and facilitates HLA-associated immune control of HIV
by: Clarety Kaseke, et al.
Published: (2021-07-01)