Human N-acetyltransferase 2 (NAT2) gene variability in Brazilian populations from different geographical areas

Human N-acetyltransferase 2 (NAT2) gene variability in Brazilian populations from different geographical areas

Introduction: Several polymorphisms altering the NAT2 activity have already been identified. The geographical distribution of NAT2 variants has been extensively studied and has been demonstrated to vary significantly among different ethnic population. Here, we describe the genetic variability of hum...

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Main Authors: Márcia Quinhones P. Lopes, Raquel Lima F. Teixeira, Pedro Hernan Cabello, José Augusto C. Nery, Anna Maria Sales, Edilbert Pellegrini Nahn J. R., Marilda Vieira Moreira, Ewalda Von Rosen Stahlke, Lia Gonçalves Possuelo, Maria Lucia R. Rossetti, Marcelo F. Rabahi, Luciana F. M. Silva, Patrícia Almeida Leme, William John Woods, Mauricio Lisboa Nobre, Maria Leide Wan-Del-Rey de Oliveira, Kazuê Narahashi, Milde Cavalcanti, Philip Noel Suffys, Sotiria Boukouvala, Maria Eugênia N. Gallo, Adalberto Rezende Santos
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Pharmacology
Subjects:
human NAT2
N-acetyltransferase 2
polymorphisms
admixed population
sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1278720/full

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