Insights Into the Role of Matrix Metalloproteinases in Cancer and its Various Therapeutic Aspects: A Review

Insights Into the Role of Matrix Metalloproteinases in Cancer and its Various Therapeutic Aspects: A Review

Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that regulate the turnover of extracellular matrix (ECM) components. Gross and La Piere discovered MMPs in 1962 during an experiment on tissue samples from a tadpole’s tail. Several subtypes of MMPs have been identified, depending on...

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Bibliographic Details
Main Authors:	Sabeena Mustafa, Sheeja Koran, Lamya AlOmair
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-09-01
Series:	Frontiers in Molecular Biosciences
Subjects:	MMPs (metalloproteinases) cancer angiogenesis stem cells ECM
Online Access:	https://www.frontiersin.org/articles/10.3389/fmolb.2022.896099/full

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