DNA Assembly‐Based Stimuli‐Responsive Systems
Abstract Stimuli‐responsive designs with exogenous stimuli enable remote and reversible control of DNA nanostructures, which break many limitations of static nanostructures and inspired development of dynamic DNA nanotechnology. Moreover, the introduction of various types of organic molecules, polym...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-07-01
|
| Series: | Advanced Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/advs.202100328 |
| _version_ | 1818666535926890496 |
|---|---|
| author | Shasha Lu Jianlei Shen Chunhai Fan Qian Li Xiurong Yang |
| author_facet | Shasha Lu Jianlei Shen Chunhai Fan Qian Li Xiurong Yang |
| author_sort | Shasha Lu |
| collection | DOAJ |
| description | Abstract Stimuli‐responsive designs with exogenous stimuli enable remote and reversible control of DNA nanostructures, which break many limitations of static nanostructures and inspired development of dynamic DNA nanotechnology. Moreover, the introduction of various types of organic molecules, polymers, chemical bonds, and chemical reactions with stimuli‐responsive properties development has greatly expand the application scope of dynamic DNA nanotechnology. Here, DNA assembly‐based stimuli‐responsive systems are reviewed, with the focus on response units and mechanisms that depend on different exogenous stimuli (DNA strand, pH, light, temperature, electricity, metal ions, etc.), and their applications in fields of nanofabrication (DNA architectures, hybrid architectures, nanomachines, and constitutional dynamic networks) and biomedical research (biosensing, bioimaging, therapeutics, and theranostics) are discussed. Finally, the opportunities and challenges for DNA assembly‐based stimuli‐responsive systems are overviewed and discussed. |
| first_indexed | 2024-12-17T06:06:05Z |
| format | Article |
| id | doaj.art-eb9848951bbf4841bb6f18b22155c6c5 |
| institution | Directory Open Access Journal |
| issn | 2198-3844 |
| language | English |
| last_indexed | 2024-12-17T06:06:05Z |
| publishDate | 2021-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advanced Science |
| spelling | doaj.art-eb9848951bbf4841bb6f18b22155c6c52022-12-21T22:00:46ZengWileyAdvanced Science2198-38442021-07-01813n/an/a10.1002/advs.202100328DNA Assembly‐Based Stimuli‐Responsive SystemsShasha Lu0Jianlei Shen1Chunhai Fan2Qian Li3Xiurong Yang4School of Chemistry and Chemical Engineering Frontiers Science Center for Transformative Molecules Institute of Translational Medicine Shanghai Jiao Tong University Shanghai 200240 ChinaSchool of Chemistry and Chemical Engineering Frontiers Science Center for Transformative Molecules Institute of Translational Medicine Shanghai Jiao Tong University Shanghai 200240 ChinaSchool of Chemistry and Chemical Engineering Frontiers Science Center for Transformative Molecules Institute of Translational Medicine Shanghai Jiao Tong University Shanghai 200240 ChinaSchool of Chemistry and Chemical Engineering Frontiers Science Center for Transformative Molecules Institute of Translational Medicine Shanghai Jiao Tong University Shanghai 200240 ChinaSchool of Chemistry and Chemical Engineering Frontiers Science Center for Transformative Molecules Institute of Translational Medicine Shanghai Jiao Tong University Shanghai 200240 ChinaAbstract Stimuli‐responsive designs with exogenous stimuli enable remote and reversible control of DNA nanostructures, which break many limitations of static nanostructures and inspired development of dynamic DNA nanotechnology. Moreover, the introduction of various types of organic molecules, polymers, chemical bonds, and chemical reactions with stimuli‐responsive properties development has greatly expand the application scope of dynamic DNA nanotechnology. Here, DNA assembly‐based stimuli‐responsive systems are reviewed, with the focus on response units and mechanisms that depend on different exogenous stimuli (DNA strand, pH, light, temperature, electricity, metal ions, etc.), and their applications in fields of nanofabrication (DNA architectures, hybrid architectures, nanomachines, and constitutional dynamic networks) and biomedical research (biosensing, bioimaging, therapeutics, and theranostics) are discussed. Finally, the opportunities and challenges for DNA assembly‐based stimuli‐responsive systems are overviewed and discussed.https://doi.org/10.1002/advs.202100328biomedical applicationsdynamic DNA nanotechnologynanofabricationstimuli‐responsive systems |
| spellingShingle | Shasha Lu Jianlei Shen Chunhai Fan Qian Li Xiurong Yang DNA Assembly‐Based Stimuli‐Responsive Systems Advanced Science biomedical applications dynamic DNA nanotechnology nanofabrication stimuli‐responsive systems |
| title | DNA Assembly‐Based Stimuli‐Responsive Systems |
| title_full | DNA Assembly‐Based Stimuli‐Responsive Systems |
| title_fullStr | DNA Assembly‐Based Stimuli‐Responsive Systems |
| title_full_unstemmed | DNA Assembly‐Based Stimuli‐Responsive Systems |
| title_short | DNA Assembly‐Based Stimuli‐Responsive Systems |
| title_sort | dna assembly based stimuli responsive systems |
| topic | biomedical applications dynamic DNA nanotechnology nanofabrication stimuli‐responsive systems |
| url | https://doi.org/10.1002/advs.202100328 |
| work_keys_str_mv | AT shashalu dnaassemblybasedstimuliresponsivesystems AT jianleishen dnaassemblybasedstimuliresponsivesystems AT chunhaifan dnaassemblybasedstimuliresponsivesystems AT qianli dnaassemblybasedstimuliresponsivesystems AT xiurongyang dnaassemblybasedstimuliresponsivesystems |