MACC1 Suppresses Cell Apoptosis in Hepatocellular Carcinoma by Targeting the HGF/c-MET/AKT Pathway

MACC1 Suppresses Cell Apoptosis in Hepatocellular Carcinoma by Targeting the HGF/c-MET/AKT Pathway

Background & Aims: To investigate the expression and prognostic value of MACC1 in patients with HCC and identify the mechanism by which MACC1 inhibits HCC cell apoptosis. Methods: MACC1 and p-AKT expression was studied using immunohistochemistry of both HCC tissues and adjacent liver tissues...

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Bibliographic Details
Main Authors: Yingmin Yao, Chanwei Dou, Zhongtang Lu, Xin Zheng, Qingguang Liu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
HGF/c-MET signaling
AKT
MACC1
Hepatocellular carcinoma
Apoptosis
Online Access:http://www.karger.com/Article/FullText/369754

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