<i>NSD1</i> Mutations and Pediatric High-Grade Gliomas: A Comparative Genomic Study in Primary and Recurrent Tumors

<i>NSD1</i> Mutations and Pediatric High-Grade Gliomas: A Comparative Genomic Study in Primary and Recurrent Tumors

Pediatric high-grade gliomas represent a heterogeneous group of tumors with a wide variety of molecular features. We performed whole exome sequencing and methylation profiling on matched primary and recurrent tumors from four pediatric patients with hemispheric high-grade gliomas. Genetic analysis s...

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Bibliographic Details
Main Authors: Antonio d’Amati, Arianna Nicolussi, Evelina Miele, Angela Mastronuzzi, Sabrina Rossi, Francesca Gianno, Francesca Romana Buttarelli, Simone Minasi, Pietro Lodeserto, Marina Paola Gardiman, Elisabetta Viscardi, Anna Coppa, Vittoria Donofrio, Isabella Giovannoni, Felice Giangaspero, Manila Antonelli
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Diagnostics
Subjects:
pediatric high-grade gliomas
hemispheric pediatric high-grade gliomas
high grade glioma H3-/IDH-wildtype
glioma
CNS tumors
molecular biology
Online Access:https://www.mdpi.com/2075-4418/13/1/78

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https://www.mdpi.com/2075-4418/13/1/78

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