Carboxymethyl pachymaran attenuates short-term stress induced depressive behaviours and over-expression of occludin and claudin-2 in the blood–brain-barrier by regulating inflammatory cytokines- JNK/ERK/p38 pathway

Carboxymethyl pachymaran attenuates short-term stress induced depressive behaviours and over-expression of occludin and claudin-2 in the blood–brain-barrier by regulating inflammatory cytokines- JNK/ERK/p38 pathway

The present study aimed to investigate the protective effect of carboxymethyl pachymaran (CMP) on the short-term stress mice model. The behavioural tests revealed the CMP treatment can improve depression-like behaviour in the mice model. Short-term stress induced over-expression of occludin and clau...

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Bibliographic Details
Main Authors: Jiatao He, Lianhua Hu, Qi Deng, Lijun Sun, Yuntao Zhao, Zhijia Fang, Chen Wang, Jian Zhao
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Journal of Functional Foods
Subjects:
Inflammation
Short-term stress
Carboxymethyl pachymaran
Blood-brain barrier
Tight junction proteins
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464623000907

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