The Tumorigenic Effect of lncRNA AFAP1‐AS1 is Mediated by Translated Peptide ATMLP Under the Control of m6A Methylation

The Tumorigenic Effect of lncRNA AFAP1‐AS1 is Mediated by Translated Peptide ATMLP Under the Control of m6A Methylation

Abstract Long noncoding RNAs (lncRNAs) in eukaryotic transcripts have long been believed to regulate various aspects of cellular processes, including carcinogenesis. Herein, it is found that lncRNA AFAP1‐AS1 encodes a conserved 90‐amino acid peptide located on mitochondria, named lncRNA AFAP1‐AS1 tr...

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Bibliographic Details
Main Authors: Hailong Pei, Yingchu Dai, Yongduo Yu, Jiaxin Tang, Zhifei Cao, Yongsheng Zhang, Bingyan Li, Jing Nie, Tom K. Hei, Guangming Zhou
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Advanced Science
Subjects:
autolysosomes
ionizing radiation
mitophagy
N6‐methyladenosine
tumorigenesis
Online Access:https://doi.org/10.1002/advs.202300314

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