Thrombus aspiration in patients with ST-elevation myocardial infarction: results of a national registry of interventional cardiology
Abstract Background We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in ‘real-world’ settings. Methods We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006–2012, Portugal...
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| Format: | Article |
| Language: | English |
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BMC
2018-04-01
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| Series: | BMC Cardiovascular Disorders |
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| Online Access: | http://link.springer.com/article/10.1186/s12872-018-0794-4 |
| _version_ | 1818140019515195392 |
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| author | Hélder Pereira Daniel Caldeira Rui Campante Teles Marco Costa Pedro Canas da Silva Vasco da Gama Ribeiro Vítor Brandão Dinis Martins Fernando Matias Francisco Pereira-Machado José Baptista Pedro Farto e Abreu Ricardo Santos António Drummond Henrique Cyrne de Carvalho João Calisto João Carlos Silva João Luís Pipa Jorge Marques Paulino Sousa Renato Fernandes Rui Cruz Ferreira Sousa Ramos Eduardo Infante Oliveira Manuel de Sousa Almeida on behalf of the investigators of Portuguese Registry on Interventional Cardiology (Registo Nacional de Cardiologia de Intervenção) |
| author_facet | Hélder Pereira Daniel Caldeira Rui Campante Teles Marco Costa Pedro Canas da Silva Vasco da Gama Ribeiro Vítor Brandão Dinis Martins Fernando Matias Francisco Pereira-Machado José Baptista Pedro Farto e Abreu Ricardo Santos António Drummond Henrique Cyrne de Carvalho João Calisto João Carlos Silva João Luís Pipa Jorge Marques Paulino Sousa Renato Fernandes Rui Cruz Ferreira Sousa Ramos Eduardo Infante Oliveira Manuel de Sousa Almeida on behalf of the investigators of Portuguese Registry on Interventional Cardiology (Registo Nacional de Cardiologia de Intervenção) |
| author_sort | Hélder Pereira |
| collection | DOAJ |
| description | Abstract Background We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in ‘real-world’ settings. Methods We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006–2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality, was analysed through adjusted odds ratio (aOR) and 95% confidence intervals (95%CI). Results We assessed data for 9458 STEMI patients that undergone P-PCI (35% treated with TA). The risk of in-hospital mortality with TA (aOR 0.93, 95%CI:0.54–1.60) was not significantly decreased. After matching patients through the propensity score, TA reduced significantly the risk of in-hospital mortality (OR 0.58, 95%CI:0.35–0.98; 3500 patients). Conclusions The whole cohort data does not support the routine use of TA in P-PCI, but the results of the propensity-score matched cohort suggests that the use of selective TA may improve the short-term risks of STEMI. |
| first_indexed | 2024-12-11T10:37:20Z |
| format | Article |
| id | doaj.art-eba87283a63e42778d6e1d32c6238148 |
| institution | Directory Open Access Journal |
| issn | 1471-2261 |
| language | English |
| last_indexed | 2024-12-11T10:37:20Z |
| publishDate | 2018-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cardiovascular Disorders |
| spelling | doaj.art-eba87283a63e42778d6e1d32c62381482022-12-22T01:10:40ZengBMCBMC Cardiovascular Disorders1471-22612018-04-011811510.1186/s12872-018-0794-4Thrombus aspiration in patients with ST-elevation myocardial infarction: results of a national registry of interventional cardiologyHélder Pereira0Daniel Caldeira1Rui Campante Teles2Marco Costa3Pedro Canas da Silva4Vasco da Gama Ribeiro5Vítor Brandão6Dinis Martins7Fernando Matias8Francisco Pereira-Machado9José Baptista10Pedro Farto e Abreu11Ricardo Santos12António Drummond13Henrique Cyrne de Carvalho14João Calisto15João Carlos Silva16João Luís Pipa17Jorge Marques18Paulino Sousa19Renato Fernandes20Rui Cruz Ferreira21Sousa Ramos22Eduardo Infante Oliveira23Manuel de Sousa Almeida24on behalf of the investigators of Portuguese Registry on Interventional Cardiology (Registo Nacional de Cardiologia de Intervenção)Serviço de Cardiologia, Hospital Garcia de Orta EPEServiço de Cardiologia, Hospital Garcia de Orta EPEHospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, EPECentro Hospitalar e Universitário de Coimbra – CHCHospital de Santa Maria, Centro Hospitalar de Lisboa Norte EPECentro Hospitalar de Vila Nova de Gaia/Espinho - Hospital Eduardo Santos SilvaHospital de Faro EPEHospital do Divino Espírito Santo de Ponta Delgada EPEHospital da Cruz Vermelha PortuguesaHospital da LuzUnidade de Intervenção Cardiovascular – AlvorHospital Professor Doutor Fernando da Fonseca EPEHospital de São Bernardo, Centro Hospitalar de Setúbal EPEHospital do FunchalHospital de Santo António, Centro Hospitalar do PortoCentro Hospitalar e Universitário de Coimbra – HUCCentro Hospitalar de São João EPEHospital de São TeotónioHospital de São MarcosHospital de Vila Real, Centro Hospitalar de Trás-os-Montes e Alto Douro EPEHospital do Espírito SantoHospital de Santa Marta, Centro Hospitalar Lisboa Central EPEHospital CUF Infante SantoRegisto Nacional de Cardiologia de Intervenção, APIC-CNCDCHospital de Santa Cruz. CHLO; Departamento de Fisiopatologia Nova Medical SchoolAbstract Background We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in ‘real-world’ settings. Methods We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006–2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality, was analysed through adjusted odds ratio (aOR) and 95% confidence intervals (95%CI). Results We assessed data for 9458 STEMI patients that undergone P-PCI (35% treated with TA). The risk of in-hospital mortality with TA (aOR 0.93, 95%CI:0.54–1.60) was not significantly decreased. After matching patients through the propensity score, TA reduced significantly the risk of in-hospital mortality (OR 0.58, 95%CI:0.35–0.98; 3500 patients). Conclusions The whole cohort data does not support the routine use of TA in P-PCI, but the results of the propensity-score matched cohort suggests that the use of selective TA may improve the short-term risks of STEMI.http://link.springer.com/article/10.1186/s12872-018-0794-4ThrombectomyThrombus aspirationMortalityPortugalPrimary PCIAngioplasty |
| spellingShingle | Hélder Pereira Daniel Caldeira Rui Campante Teles Marco Costa Pedro Canas da Silva Vasco da Gama Ribeiro Vítor Brandão Dinis Martins Fernando Matias Francisco Pereira-Machado José Baptista Pedro Farto e Abreu Ricardo Santos António Drummond Henrique Cyrne de Carvalho João Calisto João Carlos Silva João Luís Pipa Jorge Marques Paulino Sousa Renato Fernandes Rui Cruz Ferreira Sousa Ramos Eduardo Infante Oliveira Manuel de Sousa Almeida on behalf of the investigators of Portuguese Registry on Interventional Cardiology (Registo Nacional de Cardiologia de Intervenção) Thrombus aspiration in patients with ST-elevation myocardial infarction: results of a national registry of interventional cardiology BMC Cardiovascular Disorders Thrombectomy Thrombus aspiration Mortality Portugal Primary PCI Angioplasty |
| title | Thrombus aspiration in patients with ST-elevation myocardial infarction: results of a national registry of interventional cardiology |
| title_full | Thrombus aspiration in patients with ST-elevation myocardial infarction: results of a national registry of interventional cardiology |
| title_fullStr | Thrombus aspiration in patients with ST-elevation myocardial infarction: results of a national registry of interventional cardiology |
| title_full_unstemmed | Thrombus aspiration in patients with ST-elevation myocardial infarction: results of a national registry of interventional cardiology |
| title_short | Thrombus aspiration in patients with ST-elevation myocardial infarction: results of a national registry of interventional cardiology |
| title_sort | thrombus aspiration in patients with st elevation myocardial infarction results of a national registry of interventional cardiology |
| topic | Thrombectomy Thrombus aspiration Mortality Portugal Primary PCI Angioplasty |
| url | http://link.springer.com/article/10.1186/s12872-018-0794-4 |
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