Long-term social recognition memory in adult male rats: factor analysis of the social and non-social behaviors
A modified version of the intruder-resident paradigm was used to investigate if social recognition memory lasts at least 24 h. One hundred and forty-six adult male Wistar rats were used. Independent groups of rats were exposed to an intruder for 0.083, 0.5, 2, 24, or 168 h and tested 24 h after the...
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| Format: | Article |
| Language: | English |
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Associação Brasileira de Divulgação Científica
2010-07-01
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| Series: | Brazilian Journal of Medical and Biological Research |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000700009 |
| _version_ | 1818519157446017024 |
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| author | P.J. Moura S.T. Meirelles G.F. Xavier |
| author_facet | P.J. Moura S.T. Meirelles G.F. Xavier |
| author_sort | P.J. Moura |
| collection | DOAJ |
| description | A modified version of the intruder-resident paradigm was used to investigate if social recognition memory lasts at least 24 h. One hundred and forty-six adult male Wistar rats were used. Independent groups of rats were exposed to an intruder for 0.083, 0.5, 2, 24, or 168 h and tested 24 h after the first encounter with the familiar or a different conspecific. Factor analysis was employed to identify associations between behaviors and treatments. Resident rats exhibited a 24-h social recognition memory, as indicated by a 3- to 5-fold decrease in social behaviors in the second encounter with the same conspecific compared to those observed for a different conspecific, when the duration of the first encounter was 2 h or longer. It was possible to distinguish between two different categories of social behaviors and their expression depended on the duration of the first encounter. Sniffing the anogenital area (49.9% of the social behaviors), sniffing the body (17.9%), sniffing the head (3%), and following the conspecific (3.1%), exhibited mostly by resident rats, characterized social investigation and revealed long-term social recognition memory. However, dominance (23.8%) and mild aggression (2.3%), exhibited by both resident and intruders, characterized social agonistic behaviors and were not affected by memory. Differently, sniffing the environment (76.8% of the non-social behaviors) and rearing (14.3%), both exhibited mostly by adult intruder rats, characterized non-social behaviors. Together, these results show that social recognition memory in rats may last at least 24 h after a 2-h or longer exposure to the conspecific. |
| first_indexed | 2024-12-11T01:20:16Z |
| format | Article |
| id | doaj.art-eba8821308b840a8af1810bb6585e66e |
| institution | Directory Open Access Journal |
| issn | 0100-879X 1414-431X |
| language | English |
| last_indexed | 2024-12-11T01:20:16Z |
| publishDate | 2010-07-01 |
| publisher | Associação Brasileira de Divulgação Científica |
| record_format | Article |
| series | Brazilian Journal of Medical and Biological Research |
| spelling | doaj.art-eba8821308b840a8af1810bb6585e66e2022-12-22T01:25:45ZengAssociação Brasileira de Divulgação CientíficaBrazilian Journal of Medical and Biological Research0100-879X1414-431X2010-07-01437663676Long-term social recognition memory in adult male rats: factor analysis of the social and non-social behaviorsP.J. MouraS.T. MeirellesG.F. XavierA modified version of the intruder-resident paradigm was used to investigate if social recognition memory lasts at least 24 h. One hundred and forty-six adult male Wistar rats were used. Independent groups of rats were exposed to an intruder for 0.083, 0.5, 2, 24, or 168 h and tested 24 h after the first encounter with the familiar or a different conspecific. Factor analysis was employed to identify associations between behaviors and treatments. Resident rats exhibited a 24-h social recognition memory, as indicated by a 3- to 5-fold decrease in social behaviors in the second encounter with the same conspecific compared to those observed for a different conspecific, when the duration of the first encounter was 2 h or longer. It was possible to distinguish between two different categories of social behaviors and their expression depended on the duration of the first encounter. Sniffing the anogenital area (49.9% of the social behaviors), sniffing the body (17.9%), sniffing the head (3%), and following the conspecific (3.1%), exhibited mostly by resident rats, characterized social investigation and revealed long-term social recognition memory. However, dominance (23.8%) and mild aggression (2.3%), exhibited by both resident and intruders, characterized social agonistic behaviors and were not affected by memory. Differently, sniffing the environment (76.8% of the non-social behaviors) and rearing (14.3%), both exhibited mostly by adult intruder rats, characterized non-social behaviors. Together, these results show that social recognition memory in rats may last at least 24 h after a 2-h or longer exposure to the conspecific.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000700009Agonistic behaviorLong-term social recognition memoryNon-social behaviorPrincipal component analysisSocial behaviorSocial investigation |
| spellingShingle | P.J. Moura S.T. Meirelles G.F. Xavier Long-term social recognition memory in adult male rats: factor analysis of the social and non-social behaviors Brazilian Journal of Medical and Biological Research Agonistic behavior Long-term social recognition memory Non-social behavior Principal component analysis Social behavior Social investigation |
| title | Long-term social recognition memory in adult male rats: factor analysis of the social and non-social behaviors |
| title_full | Long-term social recognition memory in adult male rats: factor analysis of the social and non-social behaviors |
| title_fullStr | Long-term social recognition memory in adult male rats: factor analysis of the social and non-social behaviors |
| title_full_unstemmed | Long-term social recognition memory in adult male rats: factor analysis of the social and non-social behaviors |
| title_short | Long-term social recognition memory in adult male rats: factor analysis of the social and non-social behaviors |
| title_sort | long term social recognition memory in adult male rats factor analysis of the social and non social behaviors |
| topic | Agonistic behavior Long-term social recognition memory Non-social behavior Principal component analysis Social behavior Social investigation |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000700009 |
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