The response rate to hepatitis B vaccine in under one-year children in Gorgan, Iran
Background & Objective: Vaccination is one of the most effective ways in preventing the hepatitis B viruse. This study was done to evaluate the response rate to hepatitis B vaccine in under one-year children in Gorgan, Iran. Materials & Methods: This cross-sectional descriptive study was car...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | fas |
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Golestan University of Medical Sciences
2008-07-01
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| Series: | مجله دانشگاه علوم پزشکی گرگان |
| Subjects: | |
| Online Access: | http://goums.ac.ir/journal/browse.php?a_code=A-10-1-304&slc_lang=en&sid=1 |
| _version_ | 1828745438974443520 |
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| author | Abdolvahhab Moradi (PhD) Behnaz Khodabakhshi (MD) Ezzatollah Ghaemi (PhD) Azad Reza Mansourian (PhD) Abdoljalil Sarikhani (BAc) Mohsen Saeidi (MSc) |
| author_facet | Abdolvahhab Moradi (PhD) Behnaz Khodabakhshi (MD) Ezzatollah Ghaemi (PhD) Azad Reza Mansourian (PhD) Abdoljalil Sarikhani (BAc) Mohsen Saeidi (MSc) |
| author_sort | Abdolvahhab Moradi (PhD) |
| collection | DOAJ |
| description | Background & Objective: Vaccination is one of the most effective ways in preventing the hepatitis B viruse. This study was done to evaluate the response rate to hepatitis B vaccine in under one-year children in Gorgan, Iran. Materials & Methods: This cross-sectional descriptive study was carried out on 215, children of 7-12 month of age (55.3% male, 44.7% female), in Gorgan, northern Iran during 2006. These subjects already had received the three-time vaccination against hepatitis B. Anti-HBs, Anti-HBc and HBsAg level of these children serum were determined, using ELISA technique. Results: In 30 (14%) subject's serum, there was not detected any antibodies against the viruses. Out of 185 children positive for HBS, 4 cases belong to HBC viruses. As a whole, 86% of the samples, had more than ten international unit of HBS. The meanSD of the titred antibodies in male and female were 158.8412 and 187.5513.83 respectively. The response not to three-times vaccination in male and female were 84% and 89.9% respectively. Conclusion: This study showed that in spit of vaccination, there are cases with virus-contamination. The reasons for absence of any response to the vaccination in some of this children can be due to deficiency in the immune system, improper genetic background which can not be stimulated by that vaccination, inadequate proper conditions for the preservation of vaccine, and the type vaccine used. Also the procedure of vaccine inoculation, the vaccine preservation condition and transportation should be taken into considertion. |
| first_indexed | 2024-04-14T04:03:09Z |
| format | Article |
| id | doaj.art-eba8c94532984406a98022533579d584 |
| institution | Directory Open Access Journal |
| issn | 1562-4765 2008-4080 |
| language | fas |
| last_indexed | 2024-04-14T04:03:09Z |
| publishDate | 2008-07-01 |
| publisher | Golestan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشگاه علوم پزشکی گرگان |
| spelling | doaj.art-eba8c94532984406a98022533579d5842022-12-22T02:13:29ZfasGolestan University of Medical Sciencesمجله دانشگاه علوم پزشکی گرگان1562-47652008-40802008-07-011025053The response rate to hepatitis B vaccine in under one-year children in Gorgan, IranAbdolvahhab Moradi (PhD)0Behnaz Khodabakhshi (MD)1Ezzatollah Ghaemi (PhD)2Azad Reza Mansourian (PhD)3Abdoljalil Sarikhani (BAc)4Mohsen Saeidi (MSc)5 Background & Objective: Vaccination is one of the most effective ways in preventing the hepatitis B viruse. This study was done to evaluate the response rate to hepatitis B vaccine in under one-year children in Gorgan, Iran. Materials & Methods: This cross-sectional descriptive study was carried out on 215, children of 7-12 month of age (55.3% male, 44.7% female), in Gorgan, northern Iran during 2006. These subjects already had received the three-time vaccination against hepatitis B. Anti-HBs, Anti-HBc and HBsAg level of these children serum were determined, using ELISA technique. Results: In 30 (14%) subject's serum, there was not detected any antibodies against the viruses. Out of 185 children positive for HBS, 4 cases belong to HBC viruses. As a whole, 86% of the samples, had more than ten international unit of HBS. The meanSD of the titred antibodies in male and female were 158.8412 and 187.5513.83 respectively. The response not to three-times vaccination in male and female were 84% and 89.9% respectively. Conclusion: This study showed that in spit of vaccination, there are cases with virus-contamination. The reasons for absence of any response to the vaccination in some of this children can be due to deficiency in the immune system, improper genetic background which can not be stimulated by that vaccination, inadequate proper conditions for the preservation of vaccine, and the type vaccine used. Also the procedure of vaccine inoculation, the vaccine preservation condition and transportation should be taken into considertion.http://goums.ac.ir/journal/browse.php?a_code=A-10-1-304&slc_lang=en&sid=1HBs anti-bodyChildrenVaccinationHepatitis BGorgan |
| spellingShingle | Abdolvahhab Moradi (PhD) Behnaz Khodabakhshi (MD) Ezzatollah Ghaemi (PhD) Azad Reza Mansourian (PhD) Abdoljalil Sarikhani (BAc) Mohsen Saeidi (MSc) The response rate to hepatitis B vaccine in under one-year children in Gorgan, Iran مجله دانشگاه علوم پزشکی گرگان HBs anti-body Children Vaccination Hepatitis B Gorgan |
| title | The response rate to hepatitis B vaccine in under one-year children in Gorgan, Iran |
| title_full | The response rate to hepatitis B vaccine in under one-year children in Gorgan, Iran |
| title_fullStr | The response rate to hepatitis B vaccine in under one-year children in Gorgan, Iran |
| title_full_unstemmed | The response rate to hepatitis B vaccine in under one-year children in Gorgan, Iran |
| title_short | The response rate to hepatitis B vaccine in under one-year children in Gorgan, Iran |
| title_sort | response rate to hepatitis b vaccine in under one year children in gorgan iran |
| topic | HBs anti-body Children Vaccination Hepatitis B Gorgan |
| url | http://goums.ac.ir/journal/browse.php?a_code=A-10-1-304&slc_lang=en&sid=1 |
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