Syndecan-1 Amplifies Ovalbumin-Induced Airway Remodeling by Strengthening TGFβ1/Smad3 Action

Syndecan-1 Amplifies Ovalbumin-Induced Airway Remodeling by Strengthening TGFβ1/Smad3 Action

Syndecan-1 (SDC-1) is a transmembrane proteoglycan of heparin sulfate that can regulate various cell signal transduction pathways in the airway epithelial cells and fibroblasts. Airway epithelial cells and human bronchial fibroblasts are crucial in airway remodeling. However, the importance of SDC-1...

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Bibliographic Details
Main Authors:	Dong Zhang, Xin-rui Qiao, Wen-Jing Cui, Jin-tao Zhang, Yun Pan, Xiao-fei Liu, Liang Dong
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-10-01
Series:	Frontiers in Immunology
Subjects:	syndecan-1 ovalbumin airway remodeling TGFβ1/Smad3 signaling asthma
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.744477/full

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