Quantifying cumulative phenotypic and genomic evidence for procedural generation of metabolic network reconstructions.

Genome-scale metabolic network reconstructions (GENREs) are valuable tools for understanding microbial metabolism. The process of automatically generating GENREs includes identifying metabolic reactions supported by sufficient genomic evidence to generate a draft metabolic network. The draft GENRE i...

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Bibliographic Details
Main Authors: Thomas J Moutinho, Benjamin C Neubert, Matthew L Jenior, Jason A Papin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-02-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1009341