Aspirin resistance: clinical and molecular genetic evaluation techniques
The article discusses the issues related to the personalization of preventive measures for ischemic stroke, in particular those associated with resistance to one of the most common antiplatelet drugs, aspirin. A brief historical note on investigation of acetylsalicylic acid is provided. The paper ad...
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| Format: | Article |
| Language: | English |
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Research Center of Neurology
2017-02-01
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| Series: | Анналы клинической и экспериментальной неврологии |
| Subjects: | |
| Online Access: | https://annaly-nevrologii.com/journal/pathID/article/viewFile/71/89 |
| _version_ | 1811244239494840320 |
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| author | M. M. Tanashyan M. A. Domashenko A. A. Raskurazhev |
| author_facet | M. M. Tanashyan M. A. Domashenko A. A. Raskurazhev |
| author_sort | M. M. Tanashyan |
| collection | DOAJ |
| description | The article discusses the issues related to the personalization of preventive measures for ischemic stroke, in particular those associated with resistance to one of the most common antiplatelet drugs, aspirin. A brief historical note on investigation of acetylsalicylic acid is provided. The paper addresses the issue of etiological factors and epidemiology of aspirin resistance. Ananalysis and comparison of various techniques for evaluation ofthis phenomenon are performed. Separately, a molecular genetic aspect of the pathology is considered. In conclusion, the recommendations for overcoming tolerance to aspirin therapy are provided. |
| first_indexed | 2024-04-12T14:22:29Z |
| format | Article |
| id | doaj.art-ebb044b42cc243d99111c03ea61116e8 |
| institution | Directory Open Access Journal |
| issn | 2075-5473 2409-2533 |
| language | English |
| last_indexed | 2024-04-12T14:22:29Z |
| publishDate | 2017-02-01 |
| publisher | Research Center of Neurology |
| record_format | Article |
| series | Анналы клинической и экспериментальной неврологии |
| spelling | doaj.art-ebb044b42cc243d99111c03ea61116e82022-12-22T03:29:33ZengResearch Center of NeurologyАнналы клинической и экспериментальной неврологии2075-54732409-25332017-02-01101414610.17816/psaic7141Aspirin resistance: clinical and molecular genetic evaluation techniquesM. M. Tanashyan0M. A. Domashenko1A. A. Raskurazhev2Research Center of Neurology, MoscowResearch Center of Neurology, MoscowResearch Center of Neurology, MoscowThe article discusses the issues related to the personalization of preventive measures for ischemic stroke, in particular those associated with resistance to one of the most common antiplatelet drugs, aspirin. A brief historical note on investigation of acetylsalicylic acid is provided. The paper addresses the issue of etiological factors and epidemiology of aspirin resistance. Ananalysis and comparison of various techniques for evaluation ofthis phenomenon are performed. Separately, a molecular genetic aspect of the pathology is considered. In conclusion, the recommendations for overcoming tolerance to aspirin therapy are provided.https://annaly-nevrologii.com/journal/pathID/article/viewFile/71/89stroke preventionaspirin resistanceplatelet aggregationcerebrovascular pathology |
| spellingShingle | M. M. Tanashyan M. A. Domashenko A. A. Raskurazhev Aspirin resistance: clinical and molecular genetic evaluation techniques Анналы клинической и экспериментальной неврологии stroke prevention aspirin resistance platelet aggregation cerebrovascular pathology |
| title | Aspirin resistance: clinical and molecular genetic evaluation techniques |
| title_full | Aspirin resistance: clinical and molecular genetic evaluation techniques |
| title_fullStr | Aspirin resistance: clinical and molecular genetic evaluation techniques |
| title_full_unstemmed | Aspirin resistance: clinical and molecular genetic evaluation techniques |
| title_short | Aspirin resistance: clinical and molecular genetic evaluation techniques |
| title_sort | aspirin resistance clinical and molecular genetic evaluation techniques |
| topic | stroke prevention aspirin resistance platelet aggregation cerebrovascular pathology |
| url | https://annaly-nevrologii.com/journal/pathID/article/viewFile/71/89 |
| work_keys_str_mv | AT mmtanashyan aspirinresistanceclinicalandmoleculargeneticevaluationtechniques AT madomashenko aspirinresistanceclinicalandmoleculargeneticevaluationtechniques AT aaraskurazhev aspirinresistanceclinicalandmoleculargeneticevaluationtechniques |