Vapor Phosphorylation of Cellulose by Phosphorus Trichlo-Ride: Selective Phosphorylation of 6-Hydroxyl Function—The Synthesis of New Antimicrobial Cellulose 6-Phosphate(III)-Copper Complexes
This research is focused on a synthesis of copper-cellulose phosphates antimicrobial complexes. Vapor-phase phosphorylations of cellulose were achieved by exposing microcrystalline cellulose to phosphorus trichloride (PCl<sub>3</sub>) vapors. The cellulose-<i>O</i>-dichloroph...
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MDPI AG
2021-02-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/10/2/203 |
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| author | Marcin H. Kudzin Zdzisława Mrozińska Paweł Urbaniak |
| author_facet | Marcin H. Kudzin Zdzisława Mrozińska Paweł Urbaniak |
| author_sort | Marcin H. Kudzin |
| collection | DOAJ |
| description | This research is focused on a synthesis of copper-cellulose phosphates antimicrobial complexes. Vapor-phase phosphorylations of cellulose were achieved by exposing microcrystalline cellulose to phosphorus trichloride (PCl<sub>3</sub>) vapors. The cellulose-<i>O</i>-dichlorophosphines (Cell-<i>O</i>-PCl<sub>2</sub>) formed were hydrolyzed to cellulose-<i>O</i>-hydrogenphosphate (P(III)) (Cell-<i>O</i>-P(O)(H)(OH)), which, in turn, were converted into corresponding copper(II) complexes (Cell-<i>O</i>-P(O)(H)(OH)∙Cu<sup>2+</sup>). The analysis of the complexes Cell-<i>O</i>-P(O)(H)(OH)∙Cu<sup>2+</sup> covered: scanning electron microscopy (SEM), attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR), atomic absorption spectrometry with flame excitation (FAAS), and bioactivity tests against representative Gram-negative bacteria (<i>Escherichia coli</i>) and Gram-positive bacteria (<i>Staphylococcus aureus</i>). The antimicrobial tests of synthesized Cell-<i>O</i>-P(O)(H)(OH)∙Cu<sup>2+</sup> revealed their potential applications as an antibacterial material. |
| first_indexed | 2024-03-09T00:44:13Z |
| format | Article |
| id | doaj.art-ebb4e9224f33457db0cf01493543affa |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-09T00:44:13Z |
| publishDate | 2021-02-01 |
| publisher | MDPI AG |
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| series | Antibiotics |
| spelling | doaj.art-ebb4e9224f33457db0cf01493543affa2023-12-11T17:38:44ZengMDPI AGAntibiotics2079-63822021-02-0110220310.3390/antibiotics10020203Vapor Phosphorylation of Cellulose by Phosphorus Trichlo-Ride: Selective Phosphorylation of 6-Hydroxyl Function—The Synthesis of New Antimicrobial Cellulose 6-Phosphate(III)-Copper ComplexesMarcin H. Kudzin0Zdzisława Mrozińska1Paweł Urbaniak2Łukasiewicz Research Network—Textile Research Institute, Brzezinska 5/15, 92-103 Lodz, PolandŁukasiewicz Research Network—Textile Research Institute, Brzezinska 5/15, 92-103 Lodz, PolandFaculty of Chemistry, University of Lodz, Tamka 12, 90-136 Lodz, PolandThis research is focused on a synthesis of copper-cellulose phosphates antimicrobial complexes. Vapor-phase phosphorylations of cellulose were achieved by exposing microcrystalline cellulose to phosphorus trichloride (PCl<sub>3</sub>) vapors. The cellulose-<i>O</i>-dichlorophosphines (Cell-<i>O</i>-PCl<sub>2</sub>) formed were hydrolyzed to cellulose-<i>O</i>-hydrogenphosphate (P(III)) (Cell-<i>O</i>-P(O)(H)(OH)), which, in turn, were converted into corresponding copper(II) complexes (Cell-<i>O</i>-P(O)(H)(OH)∙Cu<sup>2+</sup>). The analysis of the complexes Cell-<i>O</i>-P(O)(H)(OH)∙Cu<sup>2+</sup> covered: scanning electron microscopy (SEM), attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR), atomic absorption spectrometry with flame excitation (FAAS), and bioactivity tests against representative Gram-negative bacteria (<i>Escherichia coli</i>) and Gram-positive bacteria (<i>Staphylococcus aureus</i>). The antimicrobial tests of synthesized Cell-<i>O</i>-P(O)(H)(OH)∙Cu<sup>2+</sup> revealed their potential applications as an antibacterial material.https://www.mdpi.com/2079-6382/10/2/203cellulosephosphorylationcellulose-<i>O</i>-hydrogenphosphates (III)cellulose-<i>O</i>-phosphates (III)abbreviations systemcopper complexes |
| spellingShingle | Marcin H. Kudzin Zdzisława Mrozińska Paweł Urbaniak Vapor Phosphorylation of Cellulose by Phosphorus Trichlo-Ride: Selective Phosphorylation of 6-Hydroxyl Function—The Synthesis of New Antimicrobial Cellulose 6-Phosphate(III)-Copper Complexes Antibiotics cellulose phosphorylation cellulose-<i>O</i>-hydrogenphosphates (III) cellulose-<i>O</i>-phosphates (III) abbreviations system copper complexes |
| title | Vapor Phosphorylation of Cellulose by Phosphorus Trichlo-Ride: Selective Phosphorylation of 6-Hydroxyl Function—The Synthesis of New Antimicrobial Cellulose 6-Phosphate(III)-Copper Complexes |
| title_full | Vapor Phosphorylation of Cellulose by Phosphorus Trichlo-Ride: Selective Phosphorylation of 6-Hydroxyl Function—The Synthesis of New Antimicrobial Cellulose 6-Phosphate(III)-Copper Complexes |
| title_fullStr | Vapor Phosphorylation of Cellulose by Phosphorus Trichlo-Ride: Selective Phosphorylation of 6-Hydroxyl Function—The Synthesis of New Antimicrobial Cellulose 6-Phosphate(III)-Copper Complexes |
| title_full_unstemmed | Vapor Phosphorylation of Cellulose by Phosphorus Trichlo-Ride: Selective Phosphorylation of 6-Hydroxyl Function—The Synthesis of New Antimicrobial Cellulose 6-Phosphate(III)-Copper Complexes |
| title_short | Vapor Phosphorylation of Cellulose by Phosphorus Trichlo-Ride: Selective Phosphorylation of 6-Hydroxyl Function—The Synthesis of New Antimicrobial Cellulose 6-Phosphate(III)-Copper Complexes |
| title_sort | vapor phosphorylation of cellulose by phosphorus trichlo ride selective phosphorylation of 6 hydroxyl function the synthesis of new antimicrobial cellulose 6 phosphate iii copper complexes |
| topic | cellulose phosphorylation cellulose-<i>O</i>-hydrogenphosphates (III) cellulose-<i>O</i>-phosphates (III) abbreviations system copper complexes |
| url | https://www.mdpi.com/2079-6382/10/2/203 |
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