Is there a difference in the outcomes of anterior cervical discectomy and fusion among female patients with different menopausal statuses?
Abstract Background The surgical outcomes of anterior cervical discectomy and fusion (ACDF) in female patients according to menopausal status remain unclear. The objective of this study was to investigate the differences in these outcomes among female patients with different menopausal statuses. Met...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2021-08-01
|
| Series: | Journal of Orthopaedic Surgery and Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13018-021-02673-2 |
| _version_ | 1818001118653841408 |
|---|---|
| author | Xing-jin Wang Hao Liu Jun-bo He Quan Gong Ying Hong Xin Rong Chen Ding Bei-yu Wang Yi Yang Yang Meng |
| author_facet | Xing-jin Wang Hao Liu Jun-bo He Quan Gong Ying Hong Xin Rong Chen Ding Bei-yu Wang Yi Yang Yang Meng |
| author_sort | Xing-jin Wang |
| collection | DOAJ |
| description | Abstract Background The surgical outcomes of anterior cervical discectomy and fusion (ACDF) in female patients according to menopausal status remain unclear. The objective of this study was to investigate the differences in these outcomes among female patients with different menopausal statuses. Methods Ninety-one patients undergoing single-level or consecutive two-level ACDF with a minimum 12-month postoperative follow-up were included in this study. There were 38 patients in the premenopausal group, 28 patients in the early postmenopausal group, and 25 patients in the late postmenopausal group. The clinical outcomes were evaluated by means of the neck disability index (NDI) scores, Japanese Orthopedic Association (JOA) scores, and visual analog scale (VAS) scores. Radiological parameters included cervical lordosis (CL), the functional spinal unit (FSU) angle, range of motion (ROM) of the total cervical spine, ROM of the FSU, anterior and posterior FSU height, implant subsidence, adjacent segment degeneration (ASD), and Hounsfield unit (HU) values. Results All groups showed significant improvements in their JOA, VAS, and NDI scores (P < 0.05). The differences in preoperative and final follow-up CL, ROM of C2-7, FSU angle, and ROM of FSU were not statistically significant among the three groups (P > 0.05). The anterior FSU height loss rate showed a significant difference (P = 0.043), while there was no difference in the posterior FSU height loss rate (P = 0.072). The fusion rates in the early and late postmenopausal groups were consistently lower than those in the premenopausal group during the follow-up period. All patients had satisfactory outcomes at the final follow-up. Conclusion There were no significant differences in clinical or other related outcomes of single-level or consecutive two-level ACDF in the long term among female patients with different menopausal statuses. However, the early bony fusion rates and anterior FSU height loss rates were poorer in late postmenopausal patients than in premenopausal or early postmenopausal patients. Hence, importance should be attached to the protection of late postmenopausal patients in the early postoperative period to guarantee solid bony fusion. |
| first_indexed | 2024-04-14T03:29:36Z |
| format | Article |
| id | doaj.art-ebb662a73d354c0a933a1e3039719fba |
| institution | Directory Open Access Journal |
| issn | 1749-799X |
| language | English |
| last_indexed | 2024-04-14T03:29:36Z |
| publishDate | 2021-08-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Orthopaedic Surgery and Research |
| spelling | doaj.art-ebb662a73d354c0a933a1e3039719fba2022-12-22T02:15:00ZengBMCJournal of Orthopaedic Surgery and Research1749-799X2021-08-0116111010.1186/s13018-021-02673-2Is there a difference in the outcomes of anterior cervical discectomy and fusion among female patients with different menopausal statuses?Xing-jin Wang0Hao Liu1Jun-bo He2Quan Gong3Ying Hong4Xin Rong5Chen Ding6Bei-yu Wang7Yi Yang8Yang Meng9Department of Orthopaedic Surgery, West China Hospital, Sichuan UniversityDepartment of Orthopaedic Surgery, West China Hospital, Sichuan UniversityDepartment of Orthopaedic Surgery, West China Hospital, Sichuan UniversityDepartment of Orthopaedic Surgery, West China Hospital, Sichuan UniversityDepartment of Operation Room, West China Hospital, Sichuan UniversityDepartment of Orthopaedic Surgery, West China Hospital, Sichuan UniversityDepartment of Orthopaedic Surgery, West China Hospital, Sichuan UniversityDepartment of Orthopaedic Surgery, West China Hospital, Sichuan UniversityDepartment of Orthopaedic Surgery, West China Hospital, Sichuan UniversityDepartment of Orthopaedic Surgery, West China Hospital, Sichuan UniversityAbstract Background The surgical outcomes of anterior cervical discectomy and fusion (ACDF) in female patients according to menopausal status remain unclear. The objective of this study was to investigate the differences in these outcomes among female patients with different menopausal statuses. Methods Ninety-one patients undergoing single-level or consecutive two-level ACDF with a minimum 12-month postoperative follow-up were included in this study. There were 38 patients in the premenopausal group, 28 patients in the early postmenopausal group, and 25 patients in the late postmenopausal group. The clinical outcomes were evaluated by means of the neck disability index (NDI) scores, Japanese Orthopedic Association (JOA) scores, and visual analog scale (VAS) scores. Radiological parameters included cervical lordosis (CL), the functional spinal unit (FSU) angle, range of motion (ROM) of the total cervical spine, ROM of the FSU, anterior and posterior FSU height, implant subsidence, adjacent segment degeneration (ASD), and Hounsfield unit (HU) values. Results All groups showed significant improvements in their JOA, VAS, and NDI scores (P < 0.05). The differences in preoperative and final follow-up CL, ROM of C2-7, FSU angle, and ROM of FSU were not statistically significant among the three groups (P > 0.05). The anterior FSU height loss rate showed a significant difference (P = 0.043), while there was no difference in the posterior FSU height loss rate (P = 0.072). The fusion rates in the early and late postmenopausal groups were consistently lower than those in the premenopausal group during the follow-up period. All patients had satisfactory outcomes at the final follow-up. Conclusion There were no significant differences in clinical or other related outcomes of single-level or consecutive two-level ACDF in the long term among female patients with different menopausal statuses. However, the early bony fusion rates and anterior FSU height loss rates were poorer in late postmenopausal patients than in premenopausal or early postmenopausal patients. Hence, importance should be attached to the protection of late postmenopausal patients in the early postoperative period to guarantee solid bony fusion.https://doi.org/10.1186/s13018-021-02673-2Anterior cervical discectomy and fusionMenopausal statusFusion ratesHeight loss |
| spellingShingle | Xing-jin Wang Hao Liu Jun-bo He Quan Gong Ying Hong Xin Rong Chen Ding Bei-yu Wang Yi Yang Yang Meng Is there a difference in the outcomes of anterior cervical discectomy and fusion among female patients with different menopausal statuses? Journal of Orthopaedic Surgery and Research Anterior cervical discectomy and fusion Menopausal status Fusion rates Height loss |
| title | Is there a difference in the outcomes of anterior cervical discectomy and fusion among female patients with different menopausal statuses? |
| title_full | Is there a difference in the outcomes of anterior cervical discectomy and fusion among female patients with different menopausal statuses? |
| title_fullStr | Is there a difference in the outcomes of anterior cervical discectomy and fusion among female patients with different menopausal statuses? |
| title_full_unstemmed | Is there a difference in the outcomes of anterior cervical discectomy and fusion among female patients with different menopausal statuses? |
| title_short | Is there a difference in the outcomes of anterior cervical discectomy and fusion among female patients with different menopausal statuses? |
| title_sort | is there a difference in the outcomes of anterior cervical discectomy and fusion among female patients with different menopausal statuses |
| topic | Anterior cervical discectomy and fusion Menopausal status Fusion rates Height loss |
| url | https://doi.org/10.1186/s13018-021-02673-2 |
| work_keys_str_mv | AT xingjinwang isthereadifferenceintheoutcomesofanteriorcervicaldiscectomyandfusionamongfemalepatientswithdifferentmenopausalstatuses AT haoliu isthereadifferenceintheoutcomesofanteriorcervicaldiscectomyandfusionamongfemalepatientswithdifferentmenopausalstatuses AT junbohe isthereadifferenceintheoutcomesofanteriorcervicaldiscectomyandfusionamongfemalepatientswithdifferentmenopausalstatuses AT quangong isthereadifferenceintheoutcomesofanteriorcervicaldiscectomyandfusionamongfemalepatientswithdifferentmenopausalstatuses AT yinghong isthereadifferenceintheoutcomesofanteriorcervicaldiscectomyandfusionamongfemalepatientswithdifferentmenopausalstatuses AT xinrong isthereadifferenceintheoutcomesofanteriorcervicaldiscectomyandfusionamongfemalepatientswithdifferentmenopausalstatuses AT chending isthereadifferenceintheoutcomesofanteriorcervicaldiscectomyandfusionamongfemalepatientswithdifferentmenopausalstatuses AT beiyuwang isthereadifferenceintheoutcomesofanteriorcervicaldiscectomyandfusionamongfemalepatientswithdifferentmenopausalstatuses AT yiyang isthereadifferenceintheoutcomesofanteriorcervicaldiscectomyandfusionamongfemalepatientswithdifferentmenopausalstatuses AT yangmeng isthereadifferenceintheoutcomesofanteriorcervicaldiscectomyandfusionamongfemalepatientswithdifferentmenopausalstatuses |