Keratinocyte FABP5-VCP complex mediates recruitment of neutrophils in psoriasis

Summary: One of the hallmarks of intractable psoriasis is neutrophil infiltration in skin lesions. However, detailed molecular mechanisms of neutrophil chemotaxis and activation remain unclear. Here, we demonstrate a significant upregulation of epidermal fatty acid binding protein (E-FABP, FABP5) in...

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Main Authors: Jiaqing Hao, Jianyu Yu, Matthew S. Yorek, Chi-Li Yu, R. Marshall Pope, Michael S. Chimenti, Yiqin Xiong, Aloysius Klingelhutz, Ali Jabbari, Bing Li
Format: Article
Jezik:English
Izdano: Elsevier 2023-11-01
Serija:Cell Reports
Teme:
Online dostop:http://www.sciencedirect.com/science/article/pii/S2211124723014614