Quantitative proteomic analysis of SARS-CoV-2 infection of primary human airway ciliated cells and lung epithelial cells demonstrates the effectiveness of SARS-CoV-2 innate immune evasion [version 1; peer review: 2 approved]

Quantitative proteomic analysis of SARS-CoV-2 infection of primary human airway ciliated cells and lung epithelial cells demonstrates the effectiveness of SARS-CoV-2 innate immune evasion [version 1; peer review: 2 approved]

Background: Quantitative proteomics is able to provide a comprehensive, unbiased description of changes to cells caused by viral infection, but interpretation may be complicated by differential changes in infected and uninfected ‘bystander’ cells, or the use of non-physiological cellular models. Met...

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Bibliographic Details
Main Authors: Paul J. Lehner, Frank McCaughan, Edward J.D. Greenwood, Thomas W.M. Crozier, Wenrui Guo, James C. Williamson, Ildar Gabaev, Linsey M. Porter, Guinevere L. Grice, Ana Teixeira-Silva, Richard J. Stanton, Arthur Wickenhagen, Sam J. Wilson, Eddie C. Y. Wang, James A. Nathan, Nicholas J. Matheson
Format: Article
Language:English
Published: Wellcome 2022-09-01
Series:Wellcome Open Research
Subjects:
SARS-CoV-2
COVID-19
Coronavirus
proteomics
eng
Online Access:https://wellcomeopenresearch.org/articles/7-224/v1

Internet

https://wellcomeopenresearch.org/articles/7-224/v1

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