Psychological and Psychosocial Interventions for PTSD, Depression and Anxiety Among Children and Adolescents in Low- and Middle-Income Countries: A Meta-Analysis

BackgroundIn low- and middle-income countries, rates of common mental health disorders are found to be very high among children and adolescents while individuals, particularly in these countries, face barriers to mental health care. In the recent years, randomized controlled trials (RCTs) have been...

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Main Authors: Jana R. Uppendahl, Cansu Alozkan-Sever, Pim Cuijpers, Ralph de Vries, Marit Sijbrandij
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fpsyt.2019.00933/full
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author Jana R. Uppendahl
Cansu Alozkan-Sever
Pim Cuijpers
Ralph de Vries
Marit Sijbrandij
author_facet Jana R. Uppendahl
Cansu Alozkan-Sever
Pim Cuijpers
Ralph de Vries
Marit Sijbrandij
author_sort Jana R. Uppendahl
collection DOAJ
description BackgroundIn low- and middle-income countries, rates of common mental health disorders are found to be very high among children and adolescents while individuals, particularly in these countries, face barriers to mental health care. In the recent years, randomized controlled trials (RCTs) have been conducted that implemented and tested different psychological and psychosocial treatment approaches to treat common mental disorders. This review aims to analyze psychological interventions among children and adolescents in low- and middle-income countries.MethodsRCTs carried out in low- and middle-income countries on psychological and psychosocial interventions for children and adolescents with symptoms of trauma- and stressor related disorders, depression or anxiety were identified in bibliographic databases. Databases were systematically searched until December 14, 2018. Effect sizes indicating differences between treatment and control groups at post-test were computed using a random-effects model. Outcomes were symptoms of depression, anxiety and posttraumatic stress disorder (PTSD).ResultsThirteen studies with a total of 2,626 participants aged between 5 and 18 years were included. Treatments varied between studies and number of treatment sessions ranged from 1 to 16. The pooled effect size, combining outcomes of depression, anxiety and PTSD of psychological or psychosocial intervention versus care-as-usual or a control conditions yielded a medium effect (g = 0.62; 95% CI: 0.27–0.98). Heterogeneity was very high (I2 = 94.41; 95% CI = 80–91). The beneficial effect of interventions increased after excluding outliers (g = 0.72; 95% CI: 0.37–1.07), while heterogeneity remained high (I2 = 86.12; 95% CI = 87–94).ConclusionHigh quality RCTs investigating the effect of psychological and psychosocial interventions on PTSD, depression and anxiety among children and adolescents in low- and middle-income countries are scarce. Results of the available studies may suggest that psychological and psychosocial interventions might be more effective in reducing symptoms of anxiety, depression and PTSD compared to control conditions. Due to very high heterogeneity, this evidence must be considered with caution.
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spelling doaj.art-ebc69174b97d4318a5d6cecf63fac0972022-12-22T01:28:01ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402020-02-011010.3389/fpsyt.2019.00933485096Psychological and Psychosocial Interventions for PTSD, Depression and Anxiety Among Children and Adolescents in Low- and Middle-Income Countries: A Meta-AnalysisJana R. Uppendahl0Cansu Alozkan-Sever1Pim Cuijpers2Ralph de Vries3Marit Sijbrandij4Department of Clinical, Neuro and Developmental Psychology, World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit, Amsterdam, NetherlandsDepartment of Clinical, Neuro and Developmental Psychology, World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit, Amsterdam, NetherlandsDepartment of Clinical, Neuro and Developmental Psychology, World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit, Amsterdam, NetherlandsMedical Library, Vrije Universiteit, Amsterdam, NetherlandsDepartment of Clinical, Neuro and Developmental Psychology, World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit, Amsterdam, NetherlandsBackgroundIn low- and middle-income countries, rates of common mental health disorders are found to be very high among children and adolescents while individuals, particularly in these countries, face barriers to mental health care. In the recent years, randomized controlled trials (RCTs) have been conducted that implemented and tested different psychological and psychosocial treatment approaches to treat common mental disorders. This review aims to analyze psychological interventions among children and adolescents in low- and middle-income countries.MethodsRCTs carried out in low- and middle-income countries on psychological and psychosocial interventions for children and adolescents with symptoms of trauma- and stressor related disorders, depression or anxiety were identified in bibliographic databases. Databases were systematically searched until December 14, 2018. Effect sizes indicating differences between treatment and control groups at post-test were computed using a random-effects model. Outcomes were symptoms of depression, anxiety and posttraumatic stress disorder (PTSD).ResultsThirteen studies with a total of 2,626 participants aged between 5 and 18 years were included. Treatments varied between studies and number of treatment sessions ranged from 1 to 16. The pooled effect size, combining outcomes of depression, anxiety and PTSD of psychological or psychosocial intervention versus care-as-usual or a control conditions yielded a medium effect (g = 0.62; 95% CI: 0.27–0.98). Heterogeneity was very high (I2 = 94.41; 95% CI = 80–91). The beneficial effect of interventions increased after excluding outliers (g = 0.72; 95% CI: 0.37–1.07), while heterogeneity remained high (I2 = 86.12; 95% CI = 87–94).ConclusionHigh quality RCTs investigating the effect of psychological and psychosocial interventions on PTSD, depression and anxiety among children and adolescents in low- and middle-income countries are scarce. Results of the available studies may suggest that psychological and psychosocial interventions might be more effective in reducing symptoms of anxiety, depression and PTSD compared to control conditions. Due to very high heterogeneity, this evidence must be considered with caution.https://www.frontiersin.org/article/10.3389/fpsyt.2019.00933/fulllow- and middle- income countrieschildrenadolescentsposttraumatic stress disorderdepressionanxiety
spellingShingle Jana R. Uppendahl
Cansu Alozkan-Sever
Pim Cuijpers
Ralph de Vries
Marit Sijbrandij
Psychological and Psychosocial Interventions for PTSD, Depression and Anxiety Among Children and Adolescents in Low- and Middle-Income Countries: A Meta-Analysis
Frontiers in Psychiatry
low- and middle- income countries
children
adolescents
posttraumatic stress disorder
depression
anxiety
title Psychological and Psychosocial Interventions for PTSD, Depression and Anxiety Among Children and Adolescents in Low- and Middle-Income Countries: A Meta-Analysis
title_full Psychological and Psychosocial Interventions for PTSD, Depression and Anxiety Among Children and Adolescents in Low- and Middle-Income Countries: A Meta-Analysis
title_fullStr Psychological and Psychosocial Interventions for PTSD, Depression and Anxiety Among Children and Adolescents in Low- and Middle-Income Countries: A Meta-Analysis
title_full_unstemmed Psychological and Psychosocial Interventions for PTSD, Depression and Anxiety Among Children and Adolescents in Low- and Middle-Income Countries: A Meta-Analysis
title_short Psychological and Psychosocial Interventions for PTSD, Depression and Anxiety Among Children and Adolescents in Low- and Middle-Income Countries: A Meta-Analysis
title_sort psychological and psychosocial interventions for ptsd depression and anxiety among children and adolescents in low and middle income countries a meta analysis
topic low- and middle- income countries
children
adolescents
posttraumatic stress disorder
depression
anxiety
url https://www.frontiersin.org/article/10.3389/fpsyt.2019.00933/full
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