Development of PARP inhibitors in advanced prostate cancer

The relatively high prevalence of alterations in the homologous recombination repair (HRR) pathway described in advanced prostate cancer provides a unique opportunity to develop therapeutic strategies that take advantage of the decreased tumor ability to repair DNA damage. Poly ADP-ribose polymerase...

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Bibliographic Details
Main Authors: Maria Teresa Bourlon, Paola Valdez, Elena Castro
Format: Article
Language:English
Published: SAGE Publishing 2024-01-01
Series:Therapeutic Advances in Medical Oncology
Online Access:https://doi.org/10.1177/17588359231221337