Diabetes insipidus in mice with a mutation in aquaporin-2.
Congenital nephrogenic diabetes insipidus (NDI) is a disease characterized by failure of the kidney to concentrate urine in response to vasopressin. Human kindreds with nephrogenic diabetes insipidus have been found to harbor mutations in the vasopressin receptor 2 (Avpr2) gene or the vasopressin-se...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2005-08-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC1189073?pdf=render |