Infection in Patients with Decompensated Heart Failure: In-Hospital Mortality and Outcome
Abstract Background: Heart failure (HF) is a syndrome, whose advanced forms have a poor prognosis, which is aggravated by the presence of comorbidities. Objective: We assessed the impact of infection in patients with decompensated HF admitted to a tertiary university-affiliated hospital in the cit...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Cardiologia (SBC)
2018-03-01
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| Series: | Arquivos Brasileiros de Cardiologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2018005003103&lng=en&tlng=en |
| _version_ | 1811204007524302848 |
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| author | Juliano Novaes Cardoso Carlos Henrique Del Carlo Mucio Tavares de Oliveira Junior Marcelo Eidi Ochiai Roberto Kalil Filho Antônio Carlos Pereira Barretto |
| author_facet | Juliano Novaes Cardoso Carlos Henrique Del Carlo Mucio Tavares de Oliveira Junior Marcelo Eidi Ochiai Roberto Kalil Filho Antônio Carlos Pereira Barretto |
| author_sort | Juliano Novaes Cardoso |
| collection | DOAJ |
| description | Abstract Background: Heart failure (HF) is a syndrome, whose advanced forms have a poor prognosis, which is aggravated by the presence of comorbidities. Objective: We assessed the impact of infection in patients with decompensated HF admitted to a tertiary university-affiliated hospital in the city of São Paulo. Methods: This study assessed 260 patients consecutively admitted to our unit because of decompensated HF. The presence of infection and other morbidities was assessed, as were in-hospital mortality and outcome after discharge. The chance of death was estimated by univariate logistic regression analysis of the variables studied. The significance level adopted was P < 0.05. Results: Of the patients studied, 54.2% were of the male sex, and the mean age ± SD was 66.1 ± 12.7 years. During hospitalization, 119 patients (45.8%) had infection: 88 (33.8%) being diagnosed with pulmonary infection and 39 patients (15.0%), with urinary infection. During hospitalization, 56 patients (21.5%) died, and, after discharge, 36 patients (17.6%). During hospitalization, 26.9% of the patients with infection died vs 17% of those without infection (p = 0.05). However, after discharge, mortality was lower in the group that had infection: 11.5% vs 22.2% (p = 0.046). Conclusions: Infection is a frequent morbidity among patients with HF admitted for compensation of the condition, and those with infection show higher in-hospital mortality. However, those patients who initially had infection and survived had a better outcome after discharge. |
| first_indexed | 2024-04-12T03:05:29Z |
| format | Article |
| id | doaj.art-ebcc96efe24842689afeebe037466c7e |
| institution | Directory Open Access Journal |
| issn | 1678-4170 |
| language | English |
| last_indexed | 2024-04-12T03:05:29Z |
| publishDate | 2018-03-01 |
| publisher | Sociedade Brasileira de Cardiologia (SBC) |
| record_format | Article |
| series | Arquivos Brasileiros de Cardiologia |
| spelling | doaj.art-ebcc96efe24842689afeebe037466c7e2022-12-22T03:50:32ZengSociedade Brasileira de Cardiologia (SBC)Arquivos Brasileiros de Cardiologia1678-41702018-03-01010.5935/abc.20180037S0066-782X2018005003103Infection in Patients with Decompensated Heart Failure: In-Hospital Mortality and OutcomeJuliano Novaes CardosoCarlos Henrique Del CarloMucio Tavares de Oliveira JuniorMarcelo Eidi OchiaiRoberto Kalil FilhoAntônio Carlos Pereira BarrettoAbstract Background: Heart failure (HF) is a syndrome, whose advanced forms have a poor prognosis, which is aggravated by the presence of comorbidities. Objective: We assessed the impact of infection in patients with decompensated HF admitted to a tertiary university-affiliated hospital in the city of São Paulo. Methods: This study assessed 260 patients consecutively admitted to our unit because of decompensated HF. The presence of infection and other morbidities was assessed, as were in-hospital mortality and outcome after discharge. The chance of death was estimated by univariate logistic regression analysis of the variables studied. The significance level adopted was P < 0.05. Results: Of the patients studied, 54.2% were of the male sex, and the mean age ± SD was 66.1 ± 12.7 years. During hospitalization, 119 patients (45.8%) had infection: 88 (33.8%) being diagnosed with pulmonary infection and 39 patients (15.0%), with urinary infection. During hospitalization, 56 patients (21.5%) died, and, after discharge, 36 patients (17.6%). During hospitalization, 26.9% of the patients with infection died vs 17% of those without infection (p = 0.05). However, after discharge, mortality was lower in the group that had infection: 11.5% vs 22.2% (p = 0.046). Conclusions: Infection is a frequent morbidity among patients with HF admitted for compensation of the condition, and those with infection show higher in-hospital mortality. However, those patients who initially had infection and survived had a better outcome after discharge.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2018005003103&lng=en&tlng=enInsuficiência Cardíaca / complicaçõesMortalidadeHospitalizaçãoComorbidadePneumopatias / complicaçõesSistema Urinário / fisiopatologia |
| spellingShingle | Juliano Novaes Cardoso Carlos Henrique Del Carlo Mucio Tavares de Oliveira Junior Marcelo Eidi Ochiai Roberto Kalil Filho Antônio Carlos Pereira Barretto Infection in Patients with Decompensated Heart Failure: In-Hospital Mortality and Outcome Arquivos Brasileiros de Cardiologia Insuficiência Cardíaca / complicações Mortalidade Hospitalização Comorbidade Pneumopatias / complicações Sistema Urinário / fisiopatologia |
| title | Infection in Patients with Decompensated Heart Failure: In-Hospital Mortality and Outcome |
| title_full | Infection in Patients with Decompensated Heart Failure: In-Hospital Mortality and Outcome |
| title_fullStr | Infection in Patients with Decompensated Heart Failure: In-Hospital Mortality and Outcome |
| title_full_unstemmed | Infection in Patients with Decompensated Heart Failure: In-Hospital Mortality and Outcome |
| title_short | Infection in Patients with Decompensated Heart Failure: In-Hospital Mortality and Outcome |
| title_sort | infection in patients with decompensated heart failure in hospital mortality and outcome |
| topic | Insuficiência Cardíaca / complicações Mortalidade Hospitalização Comorbidade Pneumopatias / complicações Sistema Urinário / fisiopatologia |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2018005003103&lng=en&tlng=en |
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