Implantation of muscle satellite cells overexpressing myogenin improves denervated muscle atrophy in rats

Implantation of muscle satellite cells overexpressing myogenin improves denervated muscle atrophy in rats

This study evaluated the effect of muscle satellite cells (MSCs) overexpressing myogenin (MyoG) on denervated muscle atrophy. Rat MSCs were isolated and transfected with the MyoG-EGFP plasmid vector GV143. MyoG-transfected MSCs (MTMs) were transplanted into rat gastrocnemius muscles at 1 week after...

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Bibliographic Details
Main Authors: H. Shen, Y. Lv, X.Q. Shen, J.H. Xu, H. Lu, L.C. Fu, T. Duan
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2016-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Denervation
Muscle atrophy
Satellite cells
Myogenin
Transplantation
Transfection
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000200609&lng=en&tlng=en

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