Sleep characteristics of persons with chronic fatigue syndrome and non-fatigued controls: results from a population-based study
<p>Abstract</p> <p>Background</p> <p>The etiology and pathophysiology of chronic fatigue syndrome (CFS) remain inchoate. Attempts to elucidate the pathophysiology must consider sleep physiology, as unrefreshing sleep is the most commonly reported of the 8 case-defining...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2006-11-01
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| Series: | BMC Neurology |
| Online Access: | http://www.biomedcentral.com/1471-2377/6/41 |
| _version_ | 1818524268179226624 |
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| author | Jones James F Decker Michael J Unger Elizabeth R Youngblood Laura Maloney Elizabeth M Heim Christine Reeves William C Rye David B |
| author_facet | Jones James F Decker Michael J Unger Elizabeth R Youngblood Laura Maloney Elizabeth M Heim Christine Reeves William C Rye David B |
| author_sort | Jones James F |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>The etiology and pathophysiology of chronic fatigue syndrome (CFS) remain inchoate. Attempts to elucidate the pathophysiology must consider sleep physiology, as unrefreshing sleep is the most commonly reported of the 8 case-defining symptoms of CFS. Although published studies have consistently reported inefficient sleep and documented a variable occurrence of previously undiagnosed primary sleep disorders, they have not identified characteristic disturbances in sleep architecture or a distinctive pattern of polysomnographic abnormalities associated with CFS.</p> <p>Methods</p> <p>This study recruited CFS cases and non-fatigued controls from a population based study of CFS in Wichita, Kansas. Participants spent two nights in the research unit of a local hospital and underwent overnight polysomnographic and daytime multiple sleep latency testing in order to characterize sleep architecture.</p> <p>Results</p> <p>Approximately 18% of persons with CFS and 7% of asymptomatic controls were diagnosed with severe primary sleep disorders and were excluded from further analysis. These rates were not significantly different. Persons with CFS had a significantly higher mean frequency of obstructive apnea per hour (p = .003); however, the difference was not clinically meaningful. Other characteristics of sleep architecture did not differ between persons with CFS and controls.</p> <p>Conclusion</p> <p>Although disordered breathing during sleep may be associated with CFS, this study generally did not provide evidence that altered sleep architecture is a critical factor in CFS. Future studies should further scrutinize the relationship between subjective sleep quality relative to objective polysomnographic measures.</p> |
| first_indexed | 2024-12-11T05:54:59Z |
| format | Article |
| id | doaj.art-ebd5c90c98c4413fa3358ef6fda1097d |
| institution | Directory Open Access Journal |
| issn | 1471-2377 |
| language | English |
| last_indexed | 2024-12-11T05:54:59Z |
| publishDate | 2006-11-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Neurology |
| spelling | doaj.art-ebd5c90c98c4413fa3358ef6fda1097d2022-12-22T01:18:43ZengBMCBMC Neurology1471-23772006-11-01614110.1186/1471-2377-6-41Sleep characteristics of persons with chronic fatigue syndrome and non-fatigued controls: results from a population-based studyJones James FDecker Michael JUnger Elizabeth RYoungblood LauraMaloney Elizabeth MHeim ChristineReeves William CRye David B<p>Abstract</p> <p>Background</p> <p>The etiology and pathophysiology of chronic fatigue syndrome (CFS) remain inchoate. Attempts to elucidate the pathophysiology must consider sleep physiology, as unrefreshing sleep is the most commonly reported of the 8 case-defining symptoms of CFS. Although published studies have consistently reported inefficient sleep and documented a variable occurrence of previously undiagnosed primary sleep disorders, they have not identified characteristic disturbances in sleep architecture or a distinctive pattern of polysomnographic abnormalities associated with CFS.</p> <p>Methods</p> <p>This study recruited CFS cases and non-fatigued controls from a population based study of CFS in Wichita, Kansas. Participants spent two nights in the research unit of a local hospital and underwent overnight polysomnographic and daytime multiple sleep latency testing in order to characterize sleep architecture.</p> <p>Results</p> <p>Approximately 18% of persons with CFS and 7% of asymptomatic controls were diagnosed with severe primary sleep disorders and were excluded from further analysis. These rates were not significantly different. Persons with CFS had a significantly higher mean frequency of obstructive apnea per hour (p = .003); however, the difference was not clinically meaningful. Other characteristics of sleep architecture did not differ between persons with CFS and controls.</p> <p>Conclusion</p> <p>Although disordered breathing during sleep may be associated with CFS, this study generally did not provide evidence that altered sleep architecture is a critical factor in CFS. Future studies should further scrutinize the relationship between subjective sleep quality relative to objective polysomnographic measures.</p>http://www.biomedcentral.com/1471-2377/6/41 |
| spellingShingle | Jones James F Decker Michael J Unger Elizabeth R Youngblood Laura Maloney Elizabeth M Heim Christine Reeves William C Rye David B Sleep characteristics of persons with chronic fatigue syndrome and non-fatigued controls: results from a population-based study BMC Neurology |
| title | Sleep characteristics of persons with chronic fatigue syndrome and non-fatigued controls: results from a population-based study |
| title_full | Sleep characteristics of persons with chronic fatigue syndrome and non-fatigued controls: results from a population-based study |
| title_fullStr | Sleep characteristics of persons with chronic fatigue syndrome and non-fatigued controls: results from a population-based study |
| title_full_unstemmed | Sleep characteristics of persons with chronic fatigue syndrome and non-fatigued controls: results from a population-based study |
| title_short | Sleep characteristics of persons with chronic fatigue syndrome and non-fatigued controls: results from a population-based study |
| title_sort | sleep characteristics of persons with chronic fatigue syndrome and non fatigued controls results from a population based study |
| url | http://www.biomedcentral.com/1471-2377/6/41 |
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