Cell Therapy in Idiopathic Pulmonary Fibrosis†
Idiopathic pulmonary fibrosis is a fatal disease with no effective or curative treatment options. In recent decades, cell-based therapies using stem cells or lung progenitor cells to regenerate lung tissue have experienced rapid growth in both preclinical animal models and translational clinical stu...
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| Format: | Article |
| Language: | English |
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MDPI AG
2018-08-01
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| Series: | Medical Sciences |
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| Online Access: | http://www.mdpi.com/2076-3271/6/3/64 |
| _version_ | 1811331309312671744 |
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| author | Anna Serrano-Mollar |
| author_facet | Anna Serrano-Mollar |
| author_sort | Anna Serrano-Mollar |
| collection | DOAJ |
| description | Idiopathic pulmonary fibrosis is a fatal disease with no effective or curative treatment options. In recent decades, cell-based therapies using stem cells or lung progenitor cells to regenerate lung tissue have experienced rapid growth in both preclinical animal models and translational clinical studies. In this review, the current knowledge of these cell therapies is summarized. Although further investigations are required, these studies indicate that cell therapies are a promising therapeutic approach for the treatment of idiopathic pulmonary fibrosis. |
| first_indexed | 2024-04-13T16:18:37Z |
| format | Article |
| id | doaj.art-ebd7141595ab4bfb954ab7a26fb14963 |
| institution | Directory Open Access Journal |
| issn | 2076-3271 |
| language | English |
| last_indexed | 2024-04-13T16:18:37Z |
| publishDate | 2018-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medical Sciences |
| spelling | doaj.art-ebd7141595ab4bfb954ab7a26fb149632022-12-22T02:40:00ZengMDPI AGMedical Sciences2076-32712018-08-01636410.3390/medsci6030064medsci6030064Cell Therapy in Idiopathic Pulmonary Fibrosis†Anna Serrano-Mollar0Departamento de Patología Experimental, Instituto de Investigaciones Biomédicas de Barcelona IIBB-CSIC-IDIBAPS, Rosselló, 161, 08036 Barcelona, SpainIdiopathic pulmonary fibrosis is a fatal disease with no effective or curative treatment options. In recent decades, cell-based therapies using stem cells or lung progenitor cells to regenerate lung tissue have experienced rapid growth in both preclinical animal models and translational clinical studies. In this review, the current knowledge of these cell therapies is summarized. Although further investigations are required, these studies indicate that cell therapies are a promising therapeutic approach for the treatment of idiopathic pulmonary fibrosis.http://www.mdpi.com/2076-3271/6/3/64cell therapystem cellslung progenitor cellspreclinical studiesbleomycinpulmonary fibrosisclinical studiesidiopathic pulmonary fibrosis |
| spellingShingle | Anna Serrano-Mollar Cell Therapy in Idiopathic Pulmonary Fibrosis† Medical Sciences cell therapy stem cells lung progenitor cells preclinical studies bleomycin pulmonary fibrosis clinical studies idiopathic pulmonary fibrosis |
| title | Cell Therapy in Idiopathic Pulmonary Fibrosis† |
| title_full | Cell Therapy in Idiopathic Pulmonary Fibrosis† |
| title_fullStr | Cell Therapy in Idiopathic Pulmonary Fibrosis† |
| title_full_unstemmed | Cell Therapy in Idiopathic Pulmonary Fibrosis† |
| title_short | Cell Therapy in Idiopathic Pulmonary Fibrosis† |
| title_sort | cell therapy in idiopathic pulmonary fibrosis† |
| topic | cell therapy stem cells lung progenitor cells preclinical studies bleomycin pulmonary fibrosis clinical studies idiopathic pulmonary fibrosis |
| url | http://www.mdpi.com/2076-3271/6/3/64 |
| work_keys_str_mv | AT annaserranomollar celltherapyinidiopathicpulmonaryfibrosis |