Is it possible to substitute the monofilament test for the Ipswich Touch Test in screening for peripheral diabetic neuropathy?
Abstract Background This study aimed to assess the agreement and efficacy of the Ipswich Touch Test compared to the monofilament test in individuals with type 2 diabetes. Materials and methods A cross-sectional and analytical study was conducted. The inclusion criteria were patients with type II dia...
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| Format: | Article |
| Language: | English |
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BMC
2020-03-01
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| Series: | Diabetology & Metabolic Syndrome |
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| Online Access: | http://link.springer.com/article/10.1186/s13098-020-00534-2 |
| _version_ | 1818851866133397504 |
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| author | Luz Marina Alfonso Dutra Mirian Conceição Moura Flaviene Alves do Prado Giselle De Oliveira Lima Manuela Costa Melo Rubens Nelson Morato Fernandez Maria Rita Carvalho Garbi Novaes |
| author_facet | Luz Marina Alfonso Dutra Mirian Conceição Moura Flaviene Alves do Prado Giselle De Oliveira Lima Manuela Costa Melo Rubens Nelson Morato Fernandez Maria Rita Carvalho Garbi Novaes |
| author_sort | Luz Marina Alfonso Dutra |
| collection | DOAJ |
| description | Abstract Background This study aimed to assess the agreement and efficacy of the Ipswich Touch Test compared to the monofilament test in individuals with type 2 diabetes. Materials and methods A cross-sectional and analytical study was conducted. The inclusion criteria were patients with type II diabetes (n = 250) who did not present ulcers or amputation in either foot. The exclusion criteria were as follows: patients who presented sequelae of cerebrovascular disease or other neurological pathologies, as well as diagnoses of malignancy, alcohol abuse, liver cirrhosis, hepatitis B, AIDS, hypothyroidism, chronic kidney disease or lupus erythaematosus, as these clinical conditions could influence or bias the results (Won and Park in Endocrinol Metab 31:230–238, 2016). Sensitivity, specificity, predictive values, likelihood ratios, and Kappa index were calculated. Other factors assessed were glycated haemoglobin and body mass index. Results Most of the participants were female (71.2%), and glycated haemoglobin (HbA1c) was greater than 7% in 54.4% of the patients. The mean age was 59.43 years, and the mean time since diagnosis was 12.38 years. The Kappa index was 0.819 (p < 0.001), and the Ipswich Touch Test had a sensitivity of 83.33%, a specificity of 97.66%, a positive predictive value of 85.71%, a negative predictive value of 97.21%, a positive likelihood ratio of 30.19%, and a negative likelihood ratio of 0.17%. The level of significance was 5% in this study. Conclusion The Ipswich Touch Test resented good agreement and efficacy compared to the gold standard—the 10 g monofilament test. |
| first_indexed | 2024-12-19T07:11:50Z |
| format | Article |
| id | doaj.art-ebd9806f5c5340dcad148300e5019566 |
| institution | Directory Open Access Journal |
| issn | 1758-5996 |
| language | English |
| last_indexed | 2024-12-19T07:11:50Z |
| publishDate | 2020-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Diabetology & Metabolic Syndrome |
| spelling | doaj.art-ebd9806f5c5340dcad148300e50195662022-12-21T20:31:11ZengBMCDiabetology & Metabolic Syndrome1758-59962020-03-011211610.1186/s13098-020-00534-2Is it possible to substitute the monofilament test for the Ipswich Touch Test in screening for peripheral diabetic neuropathy?Luz Marina Alfonso Dutra0Mirian Conceição Moura1Flaviene Alves do Prado2Giselle De Oliveira Lima3Manuela Costa Melo4Rubens Nelson Morato Fernandez5Maria Rita Carvalho Garbi Novaes6Department of HealthCenter of Neuromuscular Diseases, Hospital de Apoio de BrasiliaDepartment of HealthDepartment of HealthHigher School of Health SciencesDepartment of HealthUniversity of BrasíliaAbstract Background This study aimed to assess the agreement and efficacy of the Ipswich Touch Test compared to the monofilament test in individuals with type 2 diabetes. Materials and methods A cross-sectional and analytical study was conducted. The inclusion criteria were patients with type II diabetes (n = 250) who did not present ulcers or amputation in either foot. The exclusion criteria were as follows: patients who presented sequelae of cerebrovascular disease or other neurological pathologies, as well as diagnoses of malignancy, alcohol abuse, liver cirrhosis, hepatitis B, AIDS, hypothyroidism, chronic kidney disease or lupus erythaematosus, as these clinical conditions could influence or bias the results (Won and Park in Endocrinol Metab 31:230–238, 2016). Sensitivity, specificity, predictive values, likelihood ratios, and Kappa index were calculated. Other factors assessed were glycated haemoglobin and body mass index. Results Most of the participants were female (71.2%), and glycated haemoglobin (HbA1c) was greater than 7% in 54.4% of the patients. The mean age was 59.43 years, and the mean time since diagnosis was 12.38 years. The Kappa index was 0.819 (p < 0.001), and the Ipswich Touch Test had a sensitivity of 83.33%, a specificity of 97.66%, a positive predictive value of 85.71%, a negative predictive value of 97.21%, a positive likelihood ratio of 30.19%, and a negative likelihood ratio of 0.17%. The level of significance was 5% in this study. Conclusion The Ipswich Touch Test resented good agreement and efficacy compared to the gold standard—the 10 g monofilament test.http://link.springer.com/article/10.1186/s13098-020-00534-2Adult healthDiabetic footDiabetes mellitusDiabetes neuropathiesSecondary care |
| spellingShingle | Luz Marina Alfonso Dutra Mirian Conceição Moura Flaviene Alves do Prado Giselle De Oliveira Lima Manuela Costa Melo Rubens Nelson Morato Fernandez Maria Rita Carvalho Garbi Novaes Is it possible to substitute the monofilament test for the Ipswich Touch Test in screening for peripheral diabetic neuropathy? Diabetology & Metabolic Syndrome Adult health Diabetic foot Diabetes mellitus Diabetes neuropathies Secondary care |
| title | Is it possible to substitute the monofilament test for the Ipswich Touch Test in screening for peripheral diabetic neuropathy? |
| title_full | Is it possible to substitute the monofilament test for the Ipswich Touch Test in screening for peripheral diabetic neuropathy? |
| title_fullStr | Is it possible to substitute the monofilament test for the Ipswich Touch Test in screening for peripheral diabetic neuropathy? |
| title_full_unstemmed | Is it possible to substitute the monofilament test for the Ipswich Touch Test in screening for peripheral diabetic neuropathy? |
| title_short | Is it possible to substitute the monofilament test for the Ipswich Touch Test in screening for peripheral diabetic neuropathy? |
| title_sort | is it possible to substitute the monofilament test for the ipswich touch test in screening for peripheral diabetic neuropathy |
| topic | Adult health Diabetic foot Diabetes mellitus Diabetes neuropathies Secondary care |
| url | http://link.springer.com/article/10.1186/s13098-020-00534-2 |
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