Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease: Background, Evolution, and Current Concerns

The epidemic of bovine spongiform encephalopathy in the United Kingdom, which began in 1986 and has affected nearly 200,000 cattle, is waning to a conclusion, but leaves in its wake an outbreak of human Creutzfeldt-Jakob disease, most probably resulting from the consumption of beef products contamin...

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Main Authors: Paul Brown, Robert G. Will, Raymond Bradley, David M. Asher, Linda Detwiler
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2001-02-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/7/1/70-0006_article
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author Paul Brown
Robert G. Will
Raymond Bradley
David M. Asher
Linda Detwiler
author_facet Paul Brown
Robert G. Will
Raymond Bradley
David M. Asher
Linda Detwiler
author_sort Paul Brown
collection DOAJ
description The epidemic of bovine spongiform encephalopathy in the United Kingdom, which began in 1986 and has affected nearly 200,000 cattle, is waning to a conclusion, but leaves in its wake an outbreak of human Creutzfeldt-Jakob disease, most probably resulting from the consumption of beef products contaminated by central nervous system tissue. Although averaging only 10-15 cases a year since its first appearance in 1994, its future magnitude and geographic distribution (in countries that have imported infected British cattle or cattle products, or have endogenous BSE) cannot yet be predicted. The possibility that large numbers of apparently healthy persons might be incubating the disease raises concerns about iatrogenic transmissions through instrumentation (surgery and medical diagnostic procedures) and blood and organ donations. Government agencies in many countries continue to implement new measures to minimize this risk.of this rickettsia makes it available for use in serologic tests to determine its clinical spectrum, prevalence, and distribution.
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spelling doaj.art-ebdaaaf4d5844fc8b541568207a87e7e2022-12-22T00:47:03ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592001-02-017161610.3201/eid0701.700006Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease: Background, Evolution, and Current ConcernsPaul BrownRobert G. WillRaymond BradleyDavid M. AsherLinda DetwilerThe epidemic of bovine spongiform encephalopathy in the United Kingdom, which began in 1986 and has affected nearly 200,000 cattle, is waning to a conclusion, but leaves in its wake an outbreak of human Creutzfeldt-Jakob disease, most probably resulting from the consumption of beef products contaminated by central nervous system tissue. Although averaging only 10-15 cases a year since its first appearance in 1994, its future magnitude and geographic distribution (in countries that have imported infected British cattle or cattle products, or have endogenous BSE) cannot yet be predicted. The possibility that large numbers of apparently healthy persons might be incubating the disease raises concerns about iatrogenic transmissions through instrumentation (surgery and medical diagnostic procedures) and blood and organ donations. Government agencies in many countries continue to implement new measures to minimize this risk.of this rickettsia makes it available for use in serologic tests to determine its clinical spectrum, prevalence, and distribution.https://wwwnc.cdc.gov/eid/article/7/1/70-0006_articleRussia
spellingShingle Paul Brown
Robert G. Will
Raymond Bradley
David M. Asher
Linda Detwiler
Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease: Background, Evolution, and Current Concerns
Emerging Infectious Diseases
Russia
title Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease: Background, Evolution, and Current Concerns
title_full Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease: Background, Evolution, and Current Concerns
title_fullStr Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease: Background, Evolution, and Current Concerns
title_full_unstemmed Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease: Background, Evolution, and Current Concerns
title_short Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease: Background, Evolution, and Current Concerns
title_sort bovine spongiform encephalopathy and variant creutzfeldt jakob disease background evolution and current concerns
topic Russia
url https://wwwnc.cdc.gov/eid/article/7/1/70-0006_article
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