Regulatory effects of the JAK3/STAT1 pathway on the release of secreted phospholipase A<sub>2</sub>-IIA in microvascular endothelial cells of the injured brain

Regulatory effects of the JAK3/STAT1 pathway on the release of secreted phospholipase A<sub>2</sub>-IIA in microvascular endothelial cells of the injured brain

<p>Abstract</p> <p>Background</p> <p>Secreted phospholipase A<sub>2</sub>-IIA (sPLA<sub>2</sub>-IIA) is an inducible enzyme released under several inflammatory conditions. It has been shown that sPLA<sub>2</sub>-IIA is released from r...

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Bibliographic Details
Main Authors:	Wang Guansong, Qian Pin, Xu Zhi, Zhang Jiqiang, Wang Yaoli, Cheng Saiyu, Cai Wenqin, Qian Guisheng, Wang Changzheng, DeCoster Mark A
Format:	Article
Language:	English
Published:	BMC 2012-07-01
Series:	Journal of Neuroinflammation
Subjects:	Secreted phospholipase A<sub>2</sub>-IIA Brain microvascular endothelial cells Permeability Lipopolysaccharide Nitric oxide Inducible NO synthase JAK3 STAT1
Online Access:	http://www.jneuroinflammation.com/content/9/1/170

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