Noninvasive Electromagnetic Wave Sensing of Glucose

Diabetic patients need long-term and frequent glucose monitoring to assist in insulin intake. The current finger-prick devices are painful and costly, which places noninvasive glucose sensors in high demand. In this review paper, we list several advanced electromagnetic (EM)-wave-based technologies...

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Main Authors: Ruochong Zhang, Siyu Liu, Haoran Jin, Yunqi Luo, Zesheng Zheng, Fei Gao, Yuanjin Zheng
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/19/5/1151
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author Ruochong Zhang
Siyu Liu
Haoran Jin
Yunqi Luo
Zesheng Zheng
Fei Gao
Yuanjin Zheng
author_facet Ruochong Zhang
Siyu Liu
Haoran Jin
Yunqi Luo
Zesheng Zheng
Fei Gao
Yuanjin Zheng
author_sort Ruochong Zhang
collection DOAJ
description Diabetic patients need long-term and frequent glucose monitoring to assist in insulin intake. The current finger-prick devices are painful and costly, which places noninvasive glucose sensors in high demand. In this review paper, we list several advanced electromagnetic (EM)-wave-based technologies for noninvasive glucose measurement, including infrared (IR) spectroscopy, photoacoustic (PA) spectroscopy, Raman spectroscopy, fluorescence, optical coherence tomography (OCT), Terahertz (THz) spectroscopy, and microwave sensing. The development of each method is discussed regarding the fundamental principle, system setup, and experimental results. Despite the promising achievements that have been previously reported, no established product has obtained FDA approval or survived a marketing test. The limitations of, and prospects for, these techniques are presented at the end of this review.
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spelling doaj.art-ebe4d51f6f2f4eb8b98f8450f6442f4b2022-12-22T04:23:42ZengMDPI AGSensors1424-82202019-03-01195115110.3390/s19051151s19051151Noninvasive Electromagnetic Wave Sensing of GlucoseRuochong Zhang0Siyu Liu1Haoran Jin2Yunqi Luo3Zesheng Zheng4Fei Gao5Yuanjin Zheng6School of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798, SingaporeSchool of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798, SingaporeSchool of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798, SingaporeSchool of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798, SingaporeSchool of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798, SingaporeSchool of Information Science and Technology, ShanghaiTech University, Shanghai 201210, ChinaSchool of Electrical and Electronic Engineering, Nanyang Technological University, Singapore 639798, SingaporeDiabetic patients need long-term and frequent glucose monitoring to assist in insulin intake. The current finger-prick devices are painful and costly, which places noninvasive glucose sensors in high demand. In this review paper, we list several advanced electromagnetic (EM)-wave-based technologies for noninvasive glucose measurement, including infrared (IR) spectroscopy, photoacoustic (PA) spectroscopy, Raman spectroscopy, fluorescence, optical coherence tomography (OCT), Terahertz (THz) spectroscopy, and microwave sensing. The development of each method is discussed regarding the fundamental principle, system setup, and experimental results. Despite the promising achievements that have been previously reported, no established product has obtained FDA approval or survived a marketing test. The limitations of, and prospects for, these techniques are presented at the end of this review.http://www.mdpi.com/1424-8220/19/5/1151noninvasive glucose measurementIR spectroscopyRaman spectroscopyphotoacoustic spectroscopyTHz spectroscopymicrowave sensing
spellingShingle Ruochong Zhang
Siyu Liu
Haoran Jin
Yunqi Luo
Zesheng Zheng
Fei Gao
Yuanjin Zheng
Noninvasive Electromagnetic Wave Sensing of Glucose
Sensors
noninvasive glucose measurement
IR spectroscopy
Raman spectroscopy
photoacoustic spectroscopy
THz spectroscopy
microwave sensing
title Noninvasive Electromagnetic Wave Sensing of Glucose
title_full Noninvasive Electromagnetic Wave Sensing of Glucose
title_fullStr Noninvasive Electromagnetic Wave Sensing of Glucose
title_full_unstemmed Noninvasive Electromagnetic Wave Sensing of Glucose
title_short Noninvasive Electromagnetic Wave Sensing of Glucose
title_sort noninvasive electromagnetic wave sensing of glucose
topic noninvasive glucose measurement
IR spectroscopy
Raman spectroscopy
photoacoustic spectroscopy
THz spectroscopy
microwave sensing
url http://www.mdpi.com/1424-8220/19/5/1151
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AT haoranjin noninvasiveelectromagneticwavesensingofglucose
AT yunqiluo noninvasiveelectromagneticwavesensingofglucose
AT zeshengzheng noninvasiveelectromagneticwavesensingofglucose
AT feigao noninvasiveelectromagneticwavesensingofglucose
AT yuanjinzheng noninvasiveelectromagneticwavesensingofglucose