Potential of Mycobacterium tuberculosis chorismate mutase (Rv1885c) as a novel TLR4-mediated adjuvant for dendritic cell-based cancer immunotherapy

Potential of Mycobacterium tuberculosis chorismate mutase (Rv1885c) as a novel TLR4-mediated adjuvant for dendritic cell-based cancer immunotherapy

For clinical application by dendritic cell (DC)-based cancer immunotherapy, a proper adjuvant system to elicit a strong anticancer immune response is needed. Here, we investigated the potential of chorismate mutase (TBCM, Rv1885c), a putative Mycobacterium tuberculosis (TB) virulence factor, as an i...

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Bibliographic Details
Main Authors:	Hyein Jeong, So-Young Lee, Hyejun Seo, Dong Hyun Kim, Duhyung Lee, Bum-Joon Kim
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2022-12-01
Series:	OncoImmunology
Subjects:	mycobacterium tuberculosis chorismate mutase (tbcm) tlr4 agonist dendritic cells cancer immunotherapy adjuvant
Online Access:	http://dx.doi.org/10.1080/2162402X.2021.2023340

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