Excess cerebellar granule neurons induced by the absence of p75NTR during development elicit social behavior deficits in mice

Excess cerebellar granule neurons induced by the absence of p75NTR during development elicit social behavior deficits in mice

IntroductionRecently, the cerebellum has been implicated with non-motor functions, including cognitive and emotional behavior. Anatomical and functional studies demonstrate bidirectional cerebellar connections with brain regions involved in social cognition. Cerebellar developmental abnormalities an...

Full description

Bibliographic Details
Main Authors: Juan Pablo Zanin, Mansi A. Pandya, Diego Espinoza, Wilma J. Friedman, Michael W. Shiflett
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
p75NTR
granule cell precursor (GCPs)
neurotrophins
cerebellum
social behavior
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2023.1147597/full

Similar Items

Similar Items