Idiopathic remitting seronegative symmetrical synovitis with pitting edema syndrome with underlying history of malignancy
Key Clinical Message By reporting this case, we hope to emphasize the importance of maintaining a high index of clinical suspicion for the early recognition of RS3PE in patients presenting with atypical symptoms of PMR and underlying history of malignancy. Abstract Remitting seronegative symmetrical...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-05-01
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| Series: | Clinical Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ccr3.7330 |
| _version_ | 1797820479692603392 |
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| author | Kain Kim Charles Marvil Bhavin B. Adhyaru |
| author_facet | Kain Kim Charles Marvil Bhavin B. Adhyaru |
| author_sort | Kain Kim |
| collection | DOAJ |
| description | Key Clinical Message By reporting this case, we hope to emphasize the importance of maintaining a high index of clinical suspicion for the early recognition of RS3PE in patients presenting with atypical symptoms of PMR and underlying history of malignancy. Abstract Remitting seronegative symmetrical synovitis with pitting edema is a rare rheumatic syndrome of unknown etiology. It shares qualities with many other common rheumatological disorders such as rheumatoid arthritis and polymyalgia rheumatica, making diagnosis especially challenging. RS3PE has been speculated to be a paraneoplastic syndrome, and those cases associated with underlying malignancy have shown to respond poorly to conventional treatment. Therefore, it is advisable to routinely screen patients with malignancy and presenting with RS3PE for cancer recurrence, even if in remission. |
| first_indexed | 2024-03-13T09:38:54Z |
| format | Article |
| id | doaj.art-ebefa7a0eb944dc18fb8062fd1b124f7 |
| institution | Directory Open Access Journal |
| issn | 2050-0904 |
| language | English |
| last_indexed | 2024-03-13T09:38:54Z |
| publishDate | 2023-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj.art-ebefa7a0eb944dc18fb8062fd1b124f72023-05-25T05:58:39ZengWileyClinical Case Reports2050-09042023-05-01115n/an/a10.1002/ccr3.7330Idiopathic remitting seronegative symmetrical synovitis with pitting edema syndrome with underlying history of malignancyKain Kim0Charles Marvil1Bhavin B. Adhyaru2Division of General Internal Medicine, Department of Medicine Emory University School of Medicine Atlanta Georgia United StatesDivision of General Internal Medicine, Department of Medicine Emory University School of Medicine Atlanta Georgia United StatesDivision of General Internal Medicine, Department of Medicine Emory University School of Medicine Atlanta Georgia United StatesKey Clinical Message By reporting this case, we hope to emphasize the importance of maintaining a high index of clinical suspicion for the early recognition of RS3PE in patients presenting with atypical symptoms of PMR and underlying history of malignancy. Abstract Remitting seronegative symmetrical synovitis with pitting edema is a rare rheumatic syndrome of unknown etiology. It shares qualities with many other common rheumatological disorders such as rheumatoid arthritis and polymyalgia rheumatica, making diagnosis especially challenging. RS3PE has been speculated to be a paraneoplastic syndrome, and those cases associated with underlying malignancy have shown to respond poorly to conventional treatment. Therefore, it is advisable to routinely screen patients with malignancy and presenting with RS3PE for cancer recurrence, even if in remission.https://doi.org/10.1002/ccr3.7330arthritisedemapolymyalgia rheumaticaRS3PEseronegative arthritissynovitis |
| spellingShingle | Kain Kim Charles Marvil Bhavin B. Adhyaru Idiopathic remitting seronegative symmetrical synovitis with pitting edema syndrome with underlying history of malignancy Clinical Case Reports arthritis edema polymyalgia rheumatica RS3PE seronegative arthritis synovitis |
| title | Idiopathic remitting seronegative symmetrical synovitis with pitting edema syndrome with underlying history of malignancy |
| title_full | Idiopathic remitting seronegative symmetrical synovitis with pitting edema syndrome with underlying history of malignancy |
| title_fullStr | Idiopathic remitting seronegative symmetrical synovitis with pitting edema syndrome with underlying history of malignancy |
| title_full_unstemmed | Idiopathic remitting seronegative symmetrical synovitis with pitting edema syndrome with underlying history of malignancy |
| title_short | Idiopathic remitting seronegative symmetrical synovitis with pitting edema syndrome with underlying history of malignancy |
| title_sort | idiopathic remitting seronegative symmetrical synovitis with pitting edema syndrome with underlying history of malignancy |
| topic | arthritis edema polymyalgia rheumatica RS3PE seronegative arthritis synovitis |
| url | https://doi.org/10.1002/ccr3.7330 |
| work_keys_str_mv | AT kainkim idiopathicremittingseronegativesymmetricalsynovitiswithpittingedemasyndromewithunderlyinghistoryofmalignancy AT charlesmarvil idiopathicremittingseronegativesymmetricalsynovitiswithpittingedemasyndromewithunderlyinghistoryofmalignancy AT bhavinbadhyaru idiopathicremittingseronegativesymmetricalsynovitiswithpittingedemasyndromewithunderlyinghistoryofmalignancy |