Relationship between systolic blood pressure and all-cause mortality: a prospective study in a cohort of Chinese adults
Abstract Background The association between systolic blood pressure (SBP) and all-cause mortality in Chinese adults remains unclear. This study aimed to identify the relationship of SBP with all-cause mortality in Chinese men and women. Methods One hundred twenty-one thousand eighty-two employees of...
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| Format: | Article |
| Language: | English |
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BMC
2018-01-01
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| Series: | BMC Public Health |
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| Online Access: | http://link.springer.com/article/10.1186/s12889-017-4965-5 |
| _version_ | 1828484834135113728 |
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| author | Chunsheng Li Youren Chen Qiongbing Zheng Weiqiang Wu Zhichao Chen Lu Song Shasha An Zhifang Li Shuohua Chen S. L. Wu |
| author_facet | Chunsheng Li Youren Chen Qiongbing Zheng Weiqiang Wu Zhichao Chen Lu Song Shasha An Zhifang Li Shuohua Chen S. L. Wu |
| author_sort | Chunsheng Li |
| collection | DOAJ |
| description | Abstract Background The association between systolic blood pressure (SBP) and all-cause mortality in Chinese adults remains unclear. This study aimed to identify the relationship of SBP with all-cause mortality in Chinese men and women. Methods One hundred twenty-one thousand eighty-two employees of the Kailuan Group Corporation, aged 18 or older, who participated in physical examination from 2006 to 2007 or from 2008 to 2009, were enrolled and followed up for all-cause mortality. The information used to ascertain the outcome of death during follow-up was extracted from provincial vital statistics offices, hospitalization records from the 11 hospitals, or medical records from medical insurance companies. Results The average age was 50.06 ± 12.85 in the overall sample. Over 7 years of follow-up, 5945 participants, including 5520 men and 425 women had all-cause mortality. After multivariate adjustment, men in SBP group of <100, 120–139, 140–159, 160–179 and ≥180 mmHg had hazard ratios (HR) of 1.46 (1.14–1.86), 1.14 (1.04–1.26), 1.29 (1.16–1.44), 1.57 (1.38–1.79) and 2.07 (1.76–2.43), respectively, and displayed significantly increased risk of all-cause mortality compared to those with SBP in the range of 100–119 mmHg. Compared with the group of 100–119 mmHg, women in SBP group of 140–159, 160–179 and ≥180 mmHg had significantly greater risk with HRs of 1.44 (95% CI, 1.01–2.07), 1.63 (95% CI, 1.04–2.55) and 2.31 (95% CI, 1.27–4.20). Conclusions Either lower (<100 mmHg) or higher (>120 mmHg) SBP was associated with an increased all-cause mortality risk and a J-shaped relationship was observed between SBP and all-cause mortality in men. Only SBP exceeding 140 mmHg was related to a higher risk in women. The relationship between SBP and all-cause mortality among Chinese adults may differ by sex. |
| first_indexed | 2024-12-11T09:02:33Z |
| format | Article |
| id | doaj.art-ebf5750e6cdd4935972eb57ca139c6a1 |
| institution | Directory Open Access Journal |
| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-12-11T09:02:33Z |
| publishDate | 2018-01-01 |
| publisher | BMC |
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| series | BMC Public Health |
| spelling | doaj.art-ebf5750e6cdd4935972eb57ca139c6a12022-12-22T01:13:43ZengBMCBMC Public Health1471-24582018-01-011811910.1186/s12889-017-4965-5Relationship between systolic blood pressure and all-cause mortality: a prospective study in a cohort of Chinese adultsChunsheng Li0Youren Chen1Qiongbing Zheng2Weiqiang Wu3Zhichao Chen4Lu Song5Shasha An6Zhifang Li7Shuohua Chen8S. L. Wu9Shantou University Medical CollegeDepartment of Cardiology, Second Affiliated Hospital of Shantou University Medical CollegeShantou University Medical CollegeDepartment of Cardiology, Second Affiliated Hospital of Shantou University Medical CollegeDepartment of Cardiology, Second Affiliated Hospital of Shantou University Medical CollegeGraduate School, North China University of Science and TechnologyGraduate School, North China University of Science and TechnologyDepartment of Cardiology, Kailuan General HospitalDepartment of Cardiology, Kailuan General HospitalDepartment of Cardiology, Kailuan General HospitalAbstract Background The association between systolic blood pressure (SBP) and all-cause mortality in Chinese adults remains unclear. This study aimed to identify the relationship of SBP with all-cause mortality in Chinese men and women. Methods One hundred twenty-one thousand eighty-two employees of the Kailuan Group Corporation, aged 18 or older, who participated in physical examination from 2006 to 2007 or from 2008 to 2009, were enrolled and followed up for all-cause mortality. The information used to ascertain the outcome of death during follow-up was extracted from provincial vital statistics offices, hospitalization records from the 11 hospitals, or medical records from medical insurance companies. Results The average age was 50.06 ± 12.85 in the overall sample. Over 7 years of follow-up, 5945 participants, including 5520 men and 425 women had all-cause mortality. After multivariate adjustment, men in SBP group of <100, 120–139, 140–159, 160–179 and ≥180 mmHg had hazard ratios (HR) of 1.46 (1.14–1.86), 1.14 (1.04–1.26), 1.29 (1.16–1.44), 1.57 (1.38–1.79) and 2.07 (1.76–2.43), respectively, and displayed significantly increased risk of all-cause mortality compared to those with SBP in the range of 100–119 mmHg. Compared with the group of 100–119 mmHg, women in SBP group of 140–159, 160–179 and ≥180 mmHg had significantly greater risk with HRs of 1.44 (95% CI, 1.01–2.07), 1.63 (95% CI, 1.04–2.55) and 2.31 (95% CI, 1.27–4.20). Conclusions Either lower (<100 mmHg) or higher (>120 mmHg) SBP was associated with an increased all-cause mortality risk and a J-shaped relationship was observed between SBP and all-cause mortality in men. Only SBP exceeding 140 mmHg was related to a higher risk in women. The relationship between SBP and all-cause mortality among Chinese adults may differ by sex.http://link.springer.com/article/10.1186/s12889-017-4965-5Systolic blood pressureAll-cause mortalityJ-shaped relationshipProspective cohort studySex |
| spellingShingle | Chunsheng Li Youren Chen Qiongbing Zheng Weiqiang Wu Zhichao Chen Lu Song Shasha An Zhifang Li Shuohua Chen S. L. Wu Relationship between systolic blood pressure and all-cause mortality: a prospective study in a cohort of Chinese adults BMC Public Health Systolic blood pressure All-cause mortality J-shaped relationship Prospective cohort study Sex |
| title | Relationship between systolic blood pressure and all-cause mortality: a prospective study in a cohort of Chinese adults |
| title_full | Relationship between systolic blood pressure and all-cause mortality: a prospective study in a cohort of Chinese adults |
| title_fullStr | Relationship between systolic blood pressure and all-cause mortality: a prospective study in a cohort of Chinese adults |
| title_full_unstemmed | Relationship between systolic blood pressure and all-cause mortality: a prospective study in a cohort of Chinese adults |
| title_short | Relationship between systolic blood pressure and all-cause mortality: a prospective study in a cohort of Chinese adults |
| title_sort | relationship between systolic blood pressure and all cause mortality a prospective study in a cohort of chinese adults |
| topic | Systolic blood pressure All-cause mortality J-shaped relationship Prospective cohort study Sex |
| url | http://link.springer.com/article/10.1186/s12889-017-4965-5 |
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