Verrucous carcinoma of the esophagus: a case report and literature review
Abstract Background Verrucous carcinoma is an extremely rare form of cancer in the esophagus. Case presentation A 56-year-old woman presented with dysphagia in 2007. Endoscopic examination revealed an irregular protruding circumferential erosion in the lower thoracic esophagus, but because pathologi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2020-02-01
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| Series: | Surgical Case Reports |
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| Online Access: | https://doi.org/10.1186/s40792-020-0801-8 |
| _version_ | 1818661830232375296 |
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| author | Satoshi Tabuchi Kazuo Koyanagi Koji Nagata Soji Ozawa Shigeyuki Kawachi |
| author_facet | Satoshi Tabuchi Kazuo Koyanagi Koji Nagata Soji Ozawa Shigeyuki Kawachi |
| author_sort | Satoshi Tabuchi |
| collection | DOAJ |
| description | Abstract Background Verrucous carcinoma is an extremely rare form of cancer in the esophagus. Case presentation A 56-year-old woman presented with dysphagia in 2007. Endoscopic examination revealed an irregular protruding circumferential erosion in the lower thoracic esophagus, but because pathological examination of the biopsy specimen showed no evidence of malignancy, the status of the erosion was followed up by an upper gastrointestinal endoscopic examination every 3 months. A year later, polypoid lesions and fungal infection were observed in the eroded area, but no evidence of malignancy was detected in the biopsy specimen at the time. Eighteen months later, the polypoid lesions had increased in size, and the biopsy specimen was diagnosed as highly suspicious of well-differentiated squamous cell carcinoma. Because the patient’s condition deteriorated due to worsening of the dysphagia and weight loss, we performed a thoracoscopic esophagectomy with lymph node dissection and reconstructed the alimentary tract with a gastric tube via the posterior mediastinal route. Macroscopic examination of the resected specimen showed a white protruding lesion with an irregular surface, and histopathological examination led to a diagnosis of esophageal verrucous carcinoma without lymph node metastasis. No signs of recurrence have been observed in the 8 years since surgery. Conclusion We have reported a long-term follow-up case of verrucous carcinoma of the esophagus that was difficult to diagnose before surgery. |
| first_indexed | 2024-12-17T04:51:17Z |
| format | Article |
| id | doaj.art-ebf7371cb125406ba4ae89b305c96b8f |
| institution | Directory Open Access Journal |
| issn | 2198-7793 |
| language | English |
| last_indexed | 2024-12-17T04:51:17Z |
| publishDate | 2020-02-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj.art-ebf7371cb125406ba4ae89b305c96b8f2022-12-21T22:02:54ZengSpringerOpenSurgical Case Reports2198-77932020-02-01611810.1186/s40792-020-0801-8Verrucous carcinoma of the esophagus: a case report and literature reviewSatoshi Tabuchi0Kazuo Koyanagi1Koji Nagata2Soji Ozawa3Shigeyuki Kawachi4Department of Digestive Surgery and Transplantation Surgery, Tokyo Medical University Hachioji Medical CenterDepartment of Gastroenterological Surgery, Tokai University School of MedicineDepartment of Pathology, Saitama Medical University International Medical CenterDepartment of Gastroenterological Surgery, Tokai University School of MedicineDepartment of Digestive Surgery and Transplantation Surgery, Tokyo Medical University Hachioji Medical CenterAbstract Background Verrucous carcinoma is an extremely rare form of cancer in the esophagus. Case presentation A 56-year-old woman presented with dysphagia in 2007. Endoscopic examination revealed an irregular protruding circumferential erosion in the lower thoracic esophagus, but because pathological examination of the biopsy specimen showed no evidence of malignancy, the status of the erosion was followed up by an upper gastrointestinal endoscopic examination every 3 months. A year later, polypoid lesions and fungal infection were observed in the eroded area, but no evidence of malignancy was detected in the biopsy specimen at the time. Eighteen months later, the polypoid lesions had increased in size, and the biopsy specimen was diagnosed as highly suspicious of well-differentiated squamous cell carcinoma. Because the patient’s condition deteriorated due to worsening of the dysphagia and weight loss, we performed a thoracoscopic esophagectomy with lymph node dissection and reconstructed the alimentary tract with a gastric tube via the posterior mediastinal route. Macroscopic examination of the resected specimen showed a white protruding lesion with an irregular surface, and histopathological examination led to a diagnosis of esophageal verrucous carcinoma without lymph node metastasis. No signs of recurrence have been observed in the 8 years since surgery. Conclusion We have reported a long-term follow-up case of verrucous carcinoma of the esophagus that was difficult to diagnose before surgery.https://doi.org/10.1186/s40792-020-0801-8Esophageal carcinomaVerrucous carcinomaThoracoscopic surgery |
| spellingShingle | Satoshi Tabuchi Kazuo Koyanagi Koji Nagata Soji Ozawa Shigeyuki Kawachi Verrucous carcinoma of the esophagus: a case report and literature review Surgical Case Reports Esophageal carcinoma Verrucous carcinoma Thoracoscopic surgery |
| title | Verrucous carcinoma of the esophagus: a case report and literature review |
| title_full | Verrucous carcinoma of the esophagus: a case report and literature review |
| title_fullStr | Verrucous carcinoma of the esophagus: a case report and literature review |
| title_full_unstemmed | Verrucous carcinoma of the esophagus: a case report and literature review |
| title_short | Verrucous carcinoma of the esophagus: a case report and literature review |
| title_sort | verrucous carcinoma of the esophagus a case report and literature review |
| topic | Esophageal carcinoma Verrucous carcinoma Thoracoscopic surgery |
| url | https://doi.org/10.1186/s40792-020-0801-8 |
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