Enzyme‐Responsive Branched Glycopolymer‐Based Nanoassembly for Co‐Delivery of Paclitaxel and Akt Inhibitor toward Synergistic Therapy of Gastric Cancer

Enzyme‐Responsive Branched Glycopolymer‐Based Nanoassembly for Co‐Delivery of Paclitaxel and Akt Inhibitor toward Synergistic Therapy of Gastric Cancer

Abstract Combined chemotherapy and targeted therapy holds immense potential in the management of advanced gastric cancer (GC). GC tissues exhibit an elevated expression level of protein kinase B (AKT), which contributes to disease progression and poor chemotherapeutic responsiveness. Inhibition of A...

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Bibliographic Details
Main Authors: Xiaohai Song, Hao Cai, Zhaochen Shi, Zhiqian Li, Xiuli Zheng, Kun Yang, Qiyong Gong, Zhongwei Gu, Jiankun Hu, Kui Luo
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Advanced Science
Subjects:
branched polymers
drug delivery
enzyme‐responsive nanomedicine
gastric cancer
synergistic therapy
Online Access:https://doi.org/10.1002/advs.202306230

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